Winter is approaching, and Myne—now an apprentice priestess—must prepare for her stay at the church and the upcoming Dedication Ceremony. However, due to her immense knowledge and extraordinary amount of mana, she has garnered the attention of many dangerous people, who are willing to do anything to get their hands on Myne. To keep her safe, the Head Priest assigns Myne a bodyguard and advises her to be adopted by a noble, a decision that will force her to leave her family behind. As Myne is opposed to the idea, the Head Priest gives her an ultimatum: she can be with her family until she turns 10, but if she is deemed too unstable, she will immediately be dealt with. Placed in a tough position, Myne is uncertain about her future. Despite the twists that may lie ahead, she will do whatever she can to protect those that she loves—even if it means giving up on her dream.

Taeko Okajima is a 27-year-old, independent woman who spent her entire life in Tokyo. Looking to unwind from the rush of the big city, she decides to visit her family in the country to help out during the harvest. On the train there, Taeko vividly recalls her memories as a schoolgirl in the initial stages of puberty, as if she is on a trip with her childhood self. A young farmer named Toshio picks her up at the station, and they quickly develop a friendship. During her stay, Taeko forms strong bonds with family and friends, learning the contrasts between urban and rural life, as well as the struggles and joys of farming. Nostalgic and bittersweet, Omoide Poroporo takes on Taeko's journey as an adult woman coming to terms with her childhood dreams compared to the person she is today.

Shinichi Chiaki conquers his fear of flying, and Megumi Nodame Noda's exceptional performance at a piano competition earns her an invitation to study at the prestigious Conservatoire de Paris. The pair go to Paris together to take the next step in their careers: Chiaki as a new rising conductor under the wing of the great maestro Franz von Stresemann, and Nodame as a pupil of the esteemed piano professor Charles Auclair. But, of course, the music world is much bigger than the two of them could have ever imagined. Chiaki and Nodame, alongside old friends and new rivals, must fight and persevere to reach the dazzling musical heights that await them while never losing sight of what matters most.

In the world of Loveless, each person is born with cat ears and a tail, which disappear only if that person engages in a sexual intercourse. Because of this, they have come to symbolize virginity and innocence. Additionally, fighting is only done by fighting pairs or couples, where one is known as the Sacrifice and the other as the Fighter. The first receives the damage while the latter attacks. Ritsuka Aoyagi is a 12-year-old boy, who for some unknown reason suffers from amnesia. His brother got killed recently, and as if his life has not been hard enough lately, on his first day at the new school he gets approached by a stranger called Agatsuma Soubi, who claims to have known his late brother. Ritsuka finds out that Agatsuma and his brother used to be a fighting pair, and that Agatsuma has inherited Ritsuka now that his brother is gone. Together, they try to find the truth behind his brother's death and the organization known as the Seven Moons, which may have been responsible for it. All the while, it seems that Ritsuka and Agatsuma are becoming closer than they intended to be…