Tomboy Ryouko Ookami is a fierce boxer and the assigned bruiser of her club. Of course, no normal high school club needs a bruiser, but the Otogi Bank operates more akin to an actual bank. Here, the students can ask for favors from the club as long as they promise to return the favor in the future. Sixteen-year-old Ryoushi Morino is a shy boy, a far cry from the Otogi Bank members. To his biggest surprise, after unsuccessfully confessing to Ryouko, he inadvertently finds himself joining the club! Ookami-san to Shichinin no Nakama-tachi follows the everyday lives of the Otogi Bank members as they tackle favors that range from the mundane to the dangerous. However, since Ryoushi's sole motivation is to win Ryouko over, she doubts he will be able to have her back in a fight, especially when he can't even stand having people look at him—much less fight anyone!

Ohana Matsumae is an energetic and wild teenager residing in Tokyo with her carefree single mother. Abruptly, her mother decides to run away with her new boyfriend from debt collectors, forcing the young girl to fend for herself—as per her mother's rely only on yourself philosophy—in rural Japan, where her cold grandmother runs a small inn. Driven to adapt to the tranquil lifestyle of the countryside, Ohana experiences and deals with the challenges of working as a maid, as well as meeting and making friends with enthralling people at her new school and the inn.

One day after school, Asahi Kuromine stumbles upon the truth that Youko Shiragami, the girl he has a crush on, is actually a vampire. According to her father's rules, Youko must now quit school in order to keep her family safe. However, Asahi does not want her to go and promises that he will keep her true nature secret. Unfortunately, this turns out to be easier said than done, as Asahi is a man who is easy to read and is unable to keep any secrets to himself. And this is only the beginning of his troubles—more supernatural beings enter his life, and he is forced to protect all of their identities or face the consequences. Jitsu wa Watashi wa follows Asahi as he deals with his new friends and the unique challenges they bring, struggles to keep his mouth shut, and desperately tries to win Youko's heart in the process.

As another school year begins drawing to a close, the third-year high school students move steadily toward the next milestone of their lives: graduation. Among them are Mio Natsume, a girl burdened with lingering feelings; Hazuki Morikawa, a member of the concert band but distant from the others; and Haruto Souma, an athlete obsessed with baseball. Meanwhile, second-year student Ena Komiya seeks to revive the photography club to its former glory, refusing to let the organization be disbanded. Though this group lacks a strong connection with one another, their lives suddenly cross paths with the arrival of a third-year transfer student. While a transfer so close to graduation is unusual for most, it is business as usual for Eita Izumi. Due to his father's work, he has never been able to stay in one place for very long. But as luck would have it, their most recent relocation has returned Eita to his hometown for his final semester of high school. For better or worse, it also sparks the rekindling of old relationships left behind in the past. With graduation already causing its own share of anxieties, Eita's sudden arrival brings these students' carefree days to an abrupt end. Long-forgotten memories, deeply buried emotions, and inspiring new passions—everything is brought to light in their bittersweet final semester.