After dying a laughable and pathetic death on his way back from buying a game, high school student and recluse Kazuma Satou finds himself sitting before a beautiful but obnoxious goddess named Aqua. She provides the NEET with two options: continue on to heaven or reincarnate in every gamer's dream—a real fantasy world! Choosing to start a new life, Kazuma is quickly tasked with defeating a Demon King who is terrorizing villages. But before he goes, he can choose one item of any kind to aid him in his quest, and the future hero selects Aqua. But Kazuma has made a grave mistake—Aqua is completely useless! Unfortunately, their troubles don't end here; it turns out that living in such a world is far different from how it plays out in a game. Instead of going on a thrilling adventure, the duo must first work to pay for their living expenses. Indeed, their misfortunes have only just begun!

When Kazuma Satou died, he was given two choices: pass on to heaven or be revived in a fantasy world. After choosing the new world, the goddess Aqua tasked him with defeating the Demon King, and let him choose any weapon to aid him. Unfortunately, Kazuma chose to bring Aqua herself and has regretted the decision ever since then. Not only is he stuck with a useless deity turned party archpriest, the pair also has to make enough money for living expenses. To add to their problems, their group continued to grow as more problematic adventurers joined their ranks. Their token spellcaster, Megumin, is an explosion magic specialist who can only cast one spell once per day and refuses to learn anything else. There is also their stalwart crusader, Lalatina Ford Darkness Dustiness, a helpless masochist who makes Kazuma look pure in comparison. Kono Subarashii Sekai ni Shukufuku wo! 2 continues to follow Kazuma and the rest of his party through countless more adventures as they struggle to earn money and have to deal with one another's problematic personalities. However, things rarely go as planned, and they are often sidetracked by their own idiotic tendencies.

Unlike many schools, attending Hyakkaou Private Academy prepares students for their time in the real world. Since many of the students are the children of the richest people in the world, the academy has its quirks that separate it from all the others. By day, it is a normal school, educating its pupils in history, languages, and the like. But at night, it turns into a gambling den, educating them in the art of dealing with money and manipulating people. Money is power; those who come out on top in the games stand at the top of the school. Yumeko Jabami, a seemingly naive and beautiful transfer student, is ready to try her hand at Hyakkaou's special curriculum. Unlike the rest, she doesn't play to win, but for the thrill of the gamble, and her borderline insane way of gambling might just bring too many new cards to the table.

On the surface, the thought of Kyouko Hori and Izumi Miyamura getting along would be the last thing in people's minds. After all, Hori has a perfect combination of beauty and brains, while Miyamura appears meek and distant to his fellow classmates. However, a fateful meeting between the two lays both of their hidden selves bare. Even though she is popular at school, Hori has little time to socialize with her friends due to housework. On the other hand, Miyamura lives under the noses of his peers, his body bearing secret tattoos and piercings that make him look like a gentle delinquent. Having opposite personalities yet sharing odd similarities, the two quickly become friends and often spend time together in Hori's home. As they both emerge from their shells, they share with each other a side of themselves concealed from the outside world.