After his confrontation in the Nether with his younger brother Shou, Shinra Kusakabe's resolve to become a hero that saves lives from the flame terror strengthens. Finding a way to turn the Infernals back into people, unraveling the mystery of the Evangelist and Adolla Burst, and saving his mother and Shou—these are the goals Shinra has in mind. However, he has come to realize that attaining these goals will not be easy, especially with the imminent danger the Evangelist poses. The Evangelist's plan is clear: to gather the eight pillars—the individuals who possess Adolla Burst—and sacrifice them to recreate the Great Cataclysm from 250 years ago. Having been revealed by the First Pillar that the birth of a new pillar is approaching, Shinra is determined to protect his fellow pillars from the Evangelist. Thus, the fiery battle between the Special Fire Force and the Evangelist ignites. Together with the Special Fire Force, Shinra's fight continues as he uncovers the truth about the Great Cataclysm and the nature of Adolla Bursts, as well as the mysteries behind human combustion.

As World War II reaches its conclusion in 1945, Japan faces widespread destruction in the form of American bombings, devastating city after city. Hotaru no Haka, also known as Grave of the Fireflies, is the story of Seita and his sister Setsuko, two Japanese children whose lives are ravaged by the brutal war. They have lost their mother, their father, their home, and the prospect of a bright future—all tragic consequences of the war. Now orphaned and homeless, Seita and Setsuko have no choice but to drift across the countryside, beset by starvation and disease. Met with the apathy of adults along the way, they find that desperate circumstances can turn even the kindest of people cruel yet their youthful hope shines brightly in the face of unrelenting hardship, preventing the siblings from swiftly succumbing to an inevitable fate.

Hellsing, an organization specializing in dealing with supernatural threats, is called in to eliminate a vampire that is turning the villagers of Cheddar into ghouls. To put an end to this, the leader of the organization, Sir Integra Fairbrook Wingates Hellsing, dispatches her most formidable asset: a powerful vampire known as Alucard. Armed with only a single handgun, Alucard wreaks havoc on the monsters plaguing Cheddar. However, a young police officer, Seras Victoria, gets caught up in the chaos and becomes mortally wounded as a result. Taking pity on the girl, Alucard gives her a choice: die as a human or live on as a vampire. Seras accepts his offer and begins a new life as a member of Hellsing. Though it was her decision, Seras struggles with the fact that she is no longer human. Nevertheless, she must embrace being a creature of the night soon if she wants to survive on the front lines in the fight between humans and the supernatural.

Guts, a man who will one day be known as the Black Swordsman, is a young traveling mercenary characterized by the large greatsword he carries. He accepts jobs that offer the most money, but he never stays with one group for long—until he encounters the Band of the Falcon. Ambushed after completing a job, Guts crushes many of its members in combat. Griffith, The Band of the Falcon's leader and founder, takes an interest in Guts and duels him. While the others are no match for Guts, Griffith defeats him in one blow. Incapacitated and taken into the Band of the Falcon's camp to recover, Guts wakes up two days later. He confronts Griffith, and the two duel yet again, only this time with a condition: Guts will join the Band of the Falcon if he loses. Due to his fresh injuries, Guts loses the fight and is inducted by Griffith. In three years' time, Guts has become one of the Band of the Falcon's commanders. On the battlefield, his combat prowess is second only to Griffith as he takes on large groups of enemies all on his own. With Guts' immense strength and Griffith's leadership, the Band of the Falcon dominate every battle they partake in. But something menacing lurks in the shadows, threatening to change Guts' life forever.