After her parents were brutally murdered, school girl Sawa was taken into custody by Akai and Kanie, a pair of detectives assigned to her case. Corrupt and immoral, they train the girl to become a weapon, dangling the promise of vengeance in front of the hapless orphan. From celebrities and politicians to influential businessmen, Sawa is tasked with assassinating targets selected arbitrarily by her crooked overseers. She executes every mission without fail, and her distinctive weapon has become infamous among the city's police officers. Physically abused by Akai, who is no more righteous than her victims, Sawa begins to dream of a life unhindered by the shadow of her guardians. One day, Sawa meets Oburi, a fellow orphan and vigilante. They quickly form a bond born of desperation and disgruntlement at the unjust world, envisioning a future free from the stain of murder.

The Kaleido Stage is known throughout the world for captivating audiences with its amazing acrobatics, innovative routines, and extravagant costumes and sets. It is a place for guests to believe in magic, and Sora Naegino wants nothing more than to be a part of that magic—by becoming an acrobat for the famed circus herself. To realize her dream, she travels from Japan to California to audition for a place in the group. However, Sora learns that she needs much more than her natural talent to bring joy to the faces in the crowd. She quickly discovers just how difficult it is to be a professional performer where the stakes—and the stunts—are higher and mistakes spell danger! To put on performances worthy of the Kaleido Stage, she will need to endure rigorous training, unconventional assignments, fierce competition, and the antics of a mischievous spirit named Fool. Can Sora reach new heights, make new friends, conquer her fears, and surpass her limits to become a Kaleido Star?

Residing within Tokyo's district of Ueno are the Colors, three individuals who protect their city by performing good deeds and aiding their community. Or, at the very least, they pretend to be the city's defenders. In reality, the Colors are just three young girls: the shy Yui Akamatsu, the noisy Sacchan, and the video game-loving Kotoha, who spend their time playing make-believe and exploring the city. The Colors' activities are facilitated by the grandfatherly Daigorou Pops Kujiraoka, who uses his store's inventory of knick-knacks to entertain the rambunctious trio. Not everyone is a fan of the Colors though. The local policeman Saitou just wants to deal with his regular duties, but he often finds himself the target of the Colors' attention, having been made the villain in most of their fantasies. But despite his personal feelings, Saitou always finds the time to go along with the three girls' games. Even though the Colors do not actually defend Ueno, they definitely help brighten everyone's day.

Satoshi Sasshi Imamiya believes his life is in shambles, as only a 12-year-old can. Having lost his card collection, his childish dilemmas worsen when he learns that his childhood friend, Arumi Asahina, will be moving away. Suddenly, their issues are dashed aside for the surreal, and they find themselves transported away through bizarre worlds of science fiction, magic, and war. Any attempt to escape only catapults them into another alien land. Soon, the two come to a realization: every world is just a reimagining of their hometown. But there are two unfamiliar faces—the voluptuous Mune-mune and the elusive blue-haired Eutus—and they just might be the key to escaping their predicament. Abenobashi Mahou☆Shoutengai follows Sasshi and Arumi's comedic exploits as they desperately attempt to return home. However, when the pair unravel a tale spanning generations, they begin to wonder if the cause of their situation is more personal than they thought. Is returning home truly what they desire?