In the Sengoku period of Japan, a young orphan named Kotarou and his dog Tobimaru steal from unsuspecting villagers in order to make ends meet. However, Kotarou is forced to remain on the run when he finds himself being hunted down by assassins sent by China's Ming Dynasty for mysterious reasons not involving his petty crimes. Fortunately, the duo run into Nanashi, a ronin who has taken refuge in a small temple, when Kotarou is attacked and Tobimaru poisoned. Although the samurai saves the helpless pair from their pursuers, he feels that there is no need to help them further; but when offered a gem in exchange for his services as a bodyguard, he reluctantly accepts Kotarou's offer of employment—just until Tobimaru is healed and the two reach their destination. As the three set out on a perilous journey, it soon becomes evident that their path is riddled with danger, as the Ming Dynasty has now sent a terrifying swordsman after them to capture Kotarou and fulfill a certain prophecy.

In the not so distant future, mankind has advanced to a state where complete body transplants from flesh to machine is possible. This allows for great increases in both physical and cybernetic prowess and blurring the lines between the two worlds. However, criminals can also make full use of such technology, leading to new and sometimes, very dangerous crimes. In response to such innovative new methods, the Japanese Government has established Section 9, an independently operating police unit which deals with such highly sensitive crimes. Led by Daisuke Aramaki and Motoko Kusanagi, Section 9 deals with such crimes over the entire social spectrum, usually with success. However, when faced with a new A level hacker nicknamed The Laughing Man, the team is thrown into a dangerous cat and mouse game, following the hacker's trail as it leaves its mark on Japan.

After one of his coworkers fails to repay a debt, apathetic bum Kaiji Itou is pressured by loan sharks to settle the large sum of cash. Since Kaiji has little money and no future prospects of his own, he is unable to return what his colleague borrowed. Faced with massive financial burdens, Kaiji is given an offer to board the illustrious Espoir—it is said that one night aboard the ship, and all of your debts will be paid. What seems like a simple night of gambling quickly turns into a game of strategy and betrayal. With the losers of the tournament being subjected to a backbreaking life of indebted servitude, Kaiji must choose his actions—and allies—carefully. However, this is only the beginning of a series of gambles that will wager Kaiji's life, testing the full extent of his wits and will to survive.

After a curse turned him into a pig, World War I ace Marco Pagot becomes Porco Rosso, a mysterious bounty hunter who takes down sky pirates in the Adriatic Sea. He whiles away his days on a secluded island, rarely leaving other than to collect bounties or to visit the beautiful Gina, a songstress and owner of the Hotel Adriano. One day, while traveling to fix his faulty engine, Porco Rosso is gunned down by a young American hotshot named Donald Curtis. Thrilled at the possibility of fame, Donald boldly declares that the flying pig is dead. Not wanting to disappoint Gina, Porco Rosso flees to the famous Piccolo S.P.A. airplane company and takes out a massive loan in order to repair and improve his fighter plane. There, he is surprised to find that the chief engineer of Piccolo S.P.A. is the 17-year-old Fio Piccolo, who hungers for a chance to prove herself. With Fio's improvements, Porco Rosso prepares to challenge Donald officially and regain his honor.