Following the successful end of the Fourth Shinobi World War, Konohagakure has been enjoying a period of peace, prosperity, and extraordinary technological advancement. This is all due to the efforts of the Allied Shinobi Forces and the village's Seventh Hokage, Naruto Uzumaki. Now resembling a modern metropolis, Konohagakure has changed, particularly the life of a shinobi. Under the watchful eye of Naruto and his old comrades, a new generation of shinobi has stepped up to learn the ways of the ninja. Boruto Uzumaki is often the center of attention as the son of the Seventh Hokage. Despite having inherited Naruto's boisterous and stubborn demeanor, Boruto is considered a prodigy and is able to unleash his potential with the help of supportive friends and family. Unfortunately, this has only worsened his arrogance and his desire to surpass Naruto which, along with his father's busy lifestyle, has strained their relationship. However, a sinister force brewing within the village may threaten Boruto's carefree life. New friends and familiar faces join Boruto as a new story begins.

With the introduction of strict new morality laws, Japan has become a nation cleansed of all that is obscene and impure. By monitoring citizens using special devices worn around their necks, authorities have taken extreme measures to ensure that society remains chaste. In this world of sexual suppression, Tanukichi Okuma—son of an infamous terrorist who opposed the chastity laws—has just entered high school, offering his help to the student council in order to get close to president Anna Nishikinomiya, his childhood friend and crush. Little does he know that the vice president Ayame Kajou has a secret identity: Blue Snow, a masked criminal dedicated to spreading lewd material amongst the sheltered public—and Tanukichi has caught the girl's interest due to his father's notoriety. Soon, Tanukichi is dragged into joining her organization called SOX, where he is forced to spread obscene propaganda, helping to launch an assault against the government's oppressive rule. With their school set as the first point of attack, Tanukichi will have to do the unthinkable when he realizes that their primary target is the person he admires most.

After his relationship with Eris Boreas Greyrat reaches new heights, Rudeus Greyrat is ecstatic. Unfortunately, his joy is short-lived, as Eris suddenly abandons him to embark on her own journey. Believing that Eris has lost all interest in him, a heartbroken and depressed Rudeus sets forth to the Northern Territories. With his sole goal being to locate his mother on the vast continent, Rudeus wonders if persisting through daily life is worth the pain, falling into a robotic routine as he endlessly ruminates on his lost love. However, the dangers of the North soon prove that one cannot survive with a dulled mind. While on a quest with the party Counter Arrow, with whom he recently became acquainted, Rudeus has a brush with death—an experience that forces him to finally snap out of his despair. With his newfound teammates, Rudeus rediscovers the pleasure of daily adventuring and moves forward with his original goal of living his second lease on life to the fullest.

Every day, Naoto Hachiouji is teased relentlessly by Hayase Nagatoro, a first year student he meets one day in the library while working on his manga. After reading his story and seeing his awkward demeanor, she decides from that moment on to toy with him, even calling him Senpai in lieu of using his real name. At first, Nagatoro's relentless antics are more bothersome than anything and leave him feeling embarrassed, as he is forced to cater to her whims. However, as they spend more time together, a strange sort of friendship develops between them, and Naoto finds that life with Nagatoro can even be fun. But one thing's for sure: his days will never be dull again.