In the Sun Kingdom, sunshine is part of its citizens' everyday lives, and rain is something that they have never even heard of. However, in a faraway land called the Rain Dukedom, the weather is reversed, and everybody has the power to create rain with their voices. Livius Orvinus Ifrikia has conquered the entire world and expanded the Sun Kingdom's influence in the three short years since he was crowned king. Upon learning about the powers to create rain, Livius decides to marry Nike Remercier, one of the princesses of the Rain Dukedom. However, those outside the Sun Kingdom have spread a rumor that Livius is a cruel, ruthless, and tyrannical ruler, and as word reaches the princess, she begins to prepare herself for the worst. But when she finally meets her fiancé, Nike discovers that he is an entirely different person from what she originally expected.

Day in and day out, Kyouko Mogami works multiple jobs to support her childhood friend, Shoutarou Shou Fuwa, in his rise to stardom as an idol. She never complains about her way of life, as she is deeply infatuated with Shou and would go to the ends of the world for him. However, her heart is broken when she overhears Shou talk about how he views her as nothing more than a maid he cares little for. Angered over being used, Kyouko flies into a rage and swears to get revenge on her former crush by entering the world of showbiz to surpass him. Joining the relentless and unforgiving entertainment industry proves to be a challenge, as she continuously meets people who force her out of her comfort zone. But for the sake of vengeance, Kyouko is determined to push herself and rise to the top.

For hearing-impaired university student Yuki Itose, silence has been a natural part of life since birth. Her world is small and isolated; she commutes to campus, interacts with her best friend Rin Fujishiro, and communicates through writing and text messages—a lifestyle that offers little to no change. One day, during her commute, Yuki meets fellow student Itsuomi Nagi, a multilingual travel enthusiast and friend of Rin. When Itsuomi learns of Yuki's condition, he takes it in stride, moving Yuki's heart. From this one simple gesture, Yuki and Itsuomi's lives start changing day by day as they let each other into their own worlds.

As with its prequel, Zoku Natsume Yuujinchou is about Takashi Natsume, a boy who has had the ability to see youkai since he was young, and his bodyguard youkai Madara, nicknamed Nyanko-sensei. Natsume attempts to return names written in his Book of Friends (which he inherited from his grandmother Reiko) to youkai in his village. Throughout these adventures, he meets some youkai that are friendly, some that want to steal the Book, and some that want to kill him, as Natsume learns about himself and his relationship with these mysterious beings along the way.