In the distant future, humanity has found a way to live forever by purchasing mechanical bodies, but this way to immortality is extraordinarily expensive. An impoverished boy, Tetsurou Hoshino, desires to purchase a pass on the Galaxy Express 999—a train that travels throughout the universe—because it is said that at the end of the line, those aboard can obtain a mechanical body for free. When Tetsurou's mother is gunned down by the villainous machine-man hybrid Count Mecha, however, all seems lost. Tetsurou is then saved from certain death by the mysterious Maetel, a tall woman with blonde hair and a striking resemblance to his mother. She gives him a pass to the Galaxy Express under one condition: that they travel together. Thus, Tetsurou begins his journey across the universe to many unique planets and thrilling adventures, in hopes of being able to attain that which he most desires.

One Man vs. an Empire! Through fear and conquest, the Empire of Valdana holds the future of most of human space within its iron hands, and for generations, those hands have belonged to the Landless Lords of the ruling Tytania dynasty. But now the foundation of the empire is crumbling, pockets of rebellion are forming and when a mission sent to punish the city-state of Euriya is shockingly defeated, the man responsible becomes the target of a galaxy-wide manhunt! For Fan Hyurlick, architect of Tytania's first defeat, glory becomes desperation as his own side betrays him. Now Fan must not only save his own life, but somehow turn the tables on opponents who have whole worlds to command! (Source: Sentai Filmworks)

A.D. 2089 - 80 years have passed since Space War I changed the lives of both human and Zentraedi races. Both races are at peace on Earth when a new alien race called the Marduk appear within the Solar System. While covering the first battle between the U.N. Spacy and the Marduk fleet, SNN rookie reporter Hibiki Kanzaki discovers Ishtar, an Emulator that enhances the Marduk's combat abilities through singing. Hibiki brings Ishtar to Earth to teach her the values of life and culture. Together with ace Valkyrie pilot Silvie Gena, Hibiki and Ishtar must find a way to save Earth from total destruction at the hands of the Marduk leader Ingues. (Source: ANN)

A century of bloodshed between warring star systems has plunged nearly 200 worlds into the flames of war. Now, an uneasy truce has settled across the Astragius Galaxy... Chirico Cuvie, a special forces powered-armor pilot is suddenly transferred into a unit engaged in a secret and highly illegal mission to steal military secrets—from their own military! Now he's on the run...from his own army! Unsure of his loyalties and to cover their own tracks, Chirico is left behind to die in space. Surviving by luck, the renegade is now hunted by both the conspirators and military intelligence. He is driven by the haunting image of a mysterious and beautiful woman—the objective of their mission, and his sole clue to unraveling their treacherous scheme. But the conspirators will do anything to preserve their mysterious agenda... (Source: AnimeNfo)