It is the year 2017, and Europe is being invaded by the forces of the Holy Britannian Empire. In an attempt to combat the opposition's overwhelming pressure and put an end to the massive casualties, the army forms a special unit called Wyvern, or W-0, composed of former Japanese citizens referred to as Elevens. Recruited from ghettos, these young men and women pilot Knightmare frames—humanoid war machines—into dangerous operations where death awaits, hoping to make a name for themselves. When a European regiment attempting to recapture a crucial city is pinned down by the enemy, it's up to W-0 to bail them out. Among those selected for the rescue operation is Lieutenant Akito Hyuuga, known as Hannibal's Ghost due to his prowess on the battlefield. However, the supposed rescue mission becomes suicidal when, in an attempt to take out as many Britannians as possible, the commanding officer initiates the Knightmare's self-destruct sequence. In its aftermath, Akito finds that he is the last one standing…

Following the end of Satoshi's Hoenn journey, he travels to the Sinnoh region for his next adventure en route to becoming a Pokémon Master. Immediately upon arrival, Team Rocket makes another attempt to snatch Pikachu, only for it to fail once again. However, Pikachu has fallen deep into a forest and it's up to Satoshi to find him! Along the way, he reunites with Takeshi—a Pokémon breeder with whom he has traveled through many regions—and meets his soon-to-be rival, Shinji, a power-hungry trainer who cares little for his Pokémons' feelings. Still in search for Pikachu, Satoshi notices a powerful electric attack in the distance and heads toward it to find Pikachu with Team Rocket and Hikari—a novice trainer aiming to be the top Pokémon coordinator. After foiling Team Rocket's plans, Satoshi reunites with Pikachu and Hikari joins the group. And thus, Satoshi and his friends begin their journey through the exciting land of Sinnoh.

In Stern Bild City, those with special abilities are called NEXT, and can use their powers for good or bad. A unique organized group of NEXT appear regularly on Hero TV, where they chase down evildoers to bring limelight to their sponsors and earn Hero Points in the hopes of becoming the next King of Heroes. Kotetsu T. Kaburagi, known as Wild Tiger, is a veteran hero whose performance has been dwindling as of late, partially due to his inability to cooperate with other heroes. After a disappointing season in which most of the other heroes far outperformed Tiger, he is paired up with a brand new hero who identifies himself by his real name—Barnaby Brooks Jr. Barnaby, nicknamed Bunny by his frivolous new partner, quickly makes it clear that the two could not be more different. Though they mix as well as oil and water, Tiger and Bunny must learn to work together, both for the sake of their careers and to face the looming threats within Stern Bild.

Angelise Ikaruga Misurugi is the first princess of the noble Misurugi Empire. The kingdom has seen great power and prosperity due to the advancement of the revolutionary technology known as Mana, an abstract bending of light that has reduced the world's problems of war and pollution to a timeless peace. However, not all are blessed with the ability to wield Mana. Those who cannot are labeled Norma, outcasts of society who are considered a threat to civilization and live under constant persecution, and Angelise herself is one of many who want the Norma exterminated. But as Angelise's sixteenth birthday commences, it is discovered in a shocking revelation that she is actually a Norma. Chaos ensues, the public is outraged, and the once adored princess is exiled to Arzenal: a remote military base where Normas are forced into conscription. Now, the former royal must adapt to a harsh and vastly different lifestyle; piloting mechanical robots known as Paramail to fend off large, devastating beasts referred to as DRAGONs. However, a sinister truth about these savage creatures threatens to change everything.