Spontaneous Human Combustion: a chaotic phenomenon that has plagued humanity for years, randomly transforming ordinary people into flaming, violent creatures known as Infernals. While Infernals make up the first-generation accounts of Human Combustion, the second and third generations became known as pyrokinetics—people gifted with the ability to manipulate and control their flames while remaining human. To combat the Infernal threat and discover the cause, the Tokyo Armed Forces, Fire Defense Agency, and Holy Church of Sol produced their answer: the Special Fire Force. Young and eager third-generation pyrokinetic Shinra Kusakabe, nicknamed Devil's Footprints for his explosive ability to ignite his feet at will, becomes a member of the lively Special Fire Force Company 8. Upholding the brigade's duty to extinguish the blazing Infernals and lay their souls to rest, Shinra is determined to become a hero who will save the lives of those threatened by the flame terror. However, this is not the hero's game Shinra imagined. The Fire Force is a fractured mess of feuding brigades, abnormal Infernal sightings are increasing all over Tokyo, and a shadowy group is claiming to have answers to the strange fire that caused the death of Shinra's family 12 years ago. Faced with many obstacles within and outside the Fire Force, Shinra fights to uncover the truth behind the burning mysteries that have kept him in the dark.

With the appearance of a mysterious virus that kills everyone above the age of 13, mankind becomes enslaved by previously hidden, power-hungry vampires who emerge in order to subjugate society with the promise of protecting the survivors, in exchange for donations of their blood. Among these survivors are Yuuichirou and Mikaela Hyakuya, two young boys who are taken captive from an orphanage, along with other children whom they consider family. Discontent with being treated like livestock under the vampires' cruel reign, Mikaela hatches a rebellious escape plan that is ultimately doomed to fail. The only survivor to come out on the other side is Yuuichirou, who is found by the Moon Demon Company, a military unit dedicated to exterminating the vampires in Japan. Many years later, now a member of the Japanese Imperial Demon Army, Yuuichirou is determined to take revenge on the creatures that slaughtered his family, but at what cost? Owari no Seraph is a post-apocalyptic supernatural shounen anime that follows a young man's search for retribution, all the while battling for friendship and loyalty against seemingly impossible odds.

As the Fourth Holy Grail War rages on with no clear victor in sight, the remaining Servants and their Masters are called upon by Church supervisor Risei Kotomine, in order to band together and confront an impending threat that could unravel the Grail War and bring about the destruction of Fuyuki City. The uneasy truce soon collapses as Masters demonstrate that they will do anything in their power, no matter how despicable, to win. Seeds of doubt are sown between Kiritsugu Emiya and Saber, his Servant, as their conflicting ideologies on heroism and chivalry clash. Meanwhile, an ominous bond forms between Kirei Kotomine, who still seeks to find his purpose in life, and one of the remaining Servants. As the countdown to the end of the war reaches zero, the cost of winning begins to blur the line between victory and defeat.

The fierce battle between Meliodas, the captain of the Seven Deadly Sins, and the Great Holy Knight Hendrickson has devastating consequences. Armed with the fragments necessary for the revival of the Demon Clan, Hendrickson breaks the seal, allowing the Commandments to escape, all of whom are mighty warriors working directly under the Demon King himself. Through a mysterious connection, Meliodas instantly identifies them; likewise, the 10 Commandments, too, seem to sense his presence. As the demons leave a path of destruction in their wake, the Seven Deadly Sins must find a way to stop them before the Demon Clan drowns Britannia in blood and terror.