On the outside, Agastia is a firm specializing in entertainment, well-known for the theme park it operates. However, beneath such an exterior lies a monumental secret: Agastia is one of various highly advanced evil organizations that aim for world domination. Despite its true nature, the company boasts enticements that make it worthwhile to put up with the work environment. Led by its great leader Akashic, Agastia has recently become a frontrunner in reaching its fellow groups' common goal. Working for Agastia's Monster Development Division, Touka Kuroitsu is a researcher who primarily does fieldwork due to the eccentricities of her seniors. Kuroitsu's everyday jobs also include giving abrupt presentations and proposals, meeting ridiculous expectations for monster designs, and accompanying said monsters to face inevitable defeat by Agastia's enemies. Nevertheless, nothing will stop Kuroitsu from doing her best if it means getting the promotion she desires!

Shoutarou Hidari, a hard-boiled private investigator from the Narumi Detective Agency, lives for the sake of protecting the peace in the city of Fuuto alongside his inquisitive partner, Philip. One fine night, Shoutarou encounters a mysterious woman named Tokime, who is soon linked to several cases of homicide and theft. Shoutarou's investigation leads him to people using Gaia Memories—memory units similar to thumb drives holding vast amounts of data—to turn into formidable beasts called Dopants. While the majority of Gaia users were put down by the detective team in the past, a number of them still remain, posing a great threat to public safety. Once more, Shoutarou and Philip, Gaia users on the side of justice, must fight as Kamen Rider W—the renowned hero safeguarding Fuuto—to eradicate the nest of villainous Dopants, all while uncovering Tokime's true identity and confronting the long-forgotten past.

When Mizuki Hijiri transferred to a new school, all she wanted was to live a normal school life, but that did not prove to be the case when she met the infamous Hero Club. All of its members are boys suffering from various types of chuunibyou—Yamato Noda is a righteous hero, using his athletic abilities to perform noble deeds and protect others; Kazuhiro Nakamura claims to be the reincarnation of Touga Ryushouin, the result of the forbidden union between a demon and an angel; Tomoki Takashima is a pretty-boy otaku whose one true love is the 2D anime girl Sora; and Rei Tsukumo plays the role of a schemer, covertly pulling the strings. Dragged along as the newest member of the Hero Club, tepid Hijiri can't obtain the normalcy that she desires. But even so, despite their various quirks, their bonds of friendship are real; Hijiri's life can only get more exciting when she joins in on their delusions of grandeur!

The year is 2032, seven years after the Second Great Kanto Earthquake decimated Tokyo. Now, the city is reborn as MegaTokyo, built from the labors of mechanical beasts known as Boomers. Originally created to benefit humanity, the mysterious corporation known as Genom now produces Boomers with incredible destructive power as a new type of advanced weaponry, capable of disguising themselves as humans. The AD Police is a new special unit to counter the ever-increasing Boomer-related crimes. Overwhelmed by the sheer amount of crimes and disparity in strength, the AD Police poses little opposition to the Boomers. A mysterious vigilante force known as the Knight Sabers, wearing powersuits more advanced than the military, is the citizens' only hope for protection. Led by Sylia Stingray, Priscilla Priss Asagiri, Nene Romanova, and Linna Yamazaki, these beautiful girls take out any Boomer that steps out of line.