A new Holy Grail War is emerging in Snowfield, Nevada, where mages from around the world summon Servants, heroic spirits drawn from myth and history, to fight on their behalf. However, this war seems to differ from previous ones. The organization behind it appears to have used data from the Fuyuki Grail War for their ritual, resulting in strange happenings. Unbeknownst to most participants, this budding conflict is actually a fake Grail War. There exists another set of seven true Servants who are summoned to fight in the genuine Holy Grail War. One of these Servants is a powerful Saber-class who saves the life of Ayaka Sajou, his apparent master, after being summoned. With hidden agendas and unpredictable forces at play, the line between the fake and true Grail War becomes unclear, turning Snowfield into a dangerous battlefield.

Black Bloods and Red Bloods, vampires and humans. Despite their differences, these two races once fought together in a crusade against a formidable foe. A decade later, the vampire war hero Jirou Mochizuki, known as the Silver Blade, travels with his younger brother Kotarou to the Special Zone—a safe haven where vampires and humans live in harmony. However, their journey is suddenly faced with danger when a conflict erupts between vampire migrants and human forces from the Special Zone. With the rise of a developing conspiracy from an old enemy, Jirou will need the help of his new ally, Mimiko Compromiser Katsuragi, as well as the power of his ancient bloodline to protect what he treasures the most.

With the initiation of the Patrian civil war came the creation of half-beast, half-human soldiers—a development of the outnumbered Northerners in a desperate attempt to counter the overwhelming Southern forces. Able to quickly dominate battlefields and achieve victory with ease, the soldiers' godlike abilities earned them the name Incarnates. However, as the war raged on, the Incarnates encountered a problem involving the beasts inside them that they were unable to rectify by ordinary means. Once the war was over, mysteries and accounts of the Incarnates submitting to the misfortune of their war days surfaced. Aware of the horrors they faced during the war, Special Sergeant Major and former captain of the Incarnates Hank Henriette becomes a Beast Hunter—those who take the lives of Incarnates who have succumbed to the issues they experienced on the battlefields. After witnessing her father, a former Incarnate soldier, meet his end at the hands of one such Beast Hunter, Nancy Schaal Bancroft resolves to hunt the man who took her father's life. However, Nancy's eye-opening encounter with the Beast Hunter influences her to instead seek the reason behind her father's death and the Incarnates' problematic existence in society.

On November 23, 1957, the whole world witnessed the Federal Republic of Zirnitra's monumental achievement of sending the first live animal—a dog—to outer space. Since then, the space race between the confederacy and its competitor, the United Kingdom of Arnack, has intensified; the two countries hope to one day send humans to the cosmos above. As a dog's biology is inherently different from a human's anatomy, there is no way to perfectly identify the risks involving space travel and its effects on an individual's body without actually sending someone for observation. However, Zirnitra's government has a potential solution: to experiment on vampires, whose biological similarity to humans is too significant to ignore. Despite being forcibly taken from her home in the mountains, vampire Irina Luminesk shows no resistance and is even willing to train as a test subject. Lev Leps, a former top candidate to become the first human cosmonaut, is designated to accompany Irina and act as her guide. Through their time together, Irina and Lev begin to develop a mutual love for outer space, bringing them closer together.