By a twist of fate, a herbivorous dinosaur finds a lost egg and brings it back to her nest. When the egg hatches, however, a carnivorous dinosaur emerges. Unable to abandon the child, she names him Heart and raises him in exile alongside her own child. As Heart comes of age, he struggles to eat the same food as his family and runs away in disgrace when he learns that he cannot live properly without meat. Years later, the now feared predator Heart encounters a situation similar to his past—he spots a dinosaur egg opposite his kind. As it emerges, Heart remarks that the newborn is delicious-looking. The newborn herbivore thinks that Heart is his father and takes delicious-looking, or Umasou, as his name. Unable to eat a newborn who loves him, Heart reluctantly decides to raise Umasou as his own. As he nurtures a forbidden child like his mother before him, Heart struggles to deal with an unforgiving world and the true natures of predator and prey.

After the death of his parents, Yuuto Amakawa lives a pretty ordinary life in the city. The only problem he has to worry about while attending school alongside Rinko, his next-door neighbor, is his cat allergies. That all changes on his sixteenth birthday, when an Ayakashi—a supernatural creature—attacks him for the sins of his ancestors. Luckily, he is saved by Himari, a mysterious cat-woman with a sword, who explains that Yuuto is the scion of a family of demon-slayers, and she is there to protect him now that the charm that kept him hidden from the supernatural forces of the world has lost its power. Omamori Himari chronicles Yuuto's dealings with the various forces of the supernatural world, as well as the growing number of women that show up on his doorstep, each with their own dark desires. Will Yuuto be able to adjust to his new exciting environment? Or will the ghost of his (ancestor's) past catch up with him?

Due to his father's job, 15-year-old Hiroshi Kuzumi and his family move to the mountain town of Jouga. While some teenagers might have to worry about fitting in or feel out of place in a new environment, Hiroshi is welcomed enthusiastically at school by most of his new classmates. In fact, it seems like they just can't get enough of him, and he makes two friends rather quickly: the clingy and overly-affectionate Isuzu Tsumuhana, who is also his neighbor; and Kaname Asagiri, who also recently moved to Jouga. All in all, Hiroshi's new life seems to be quite normal—until people start disappearing. Hiroshi is told that the missing townsfolk have simply moved away or suddenly transferred, but he can't shake the feeling that something is wrong. Meanwhile, in the dead of night under a red moon, masked individuals led by a girl with a scythe stalk their prey in the darkened streets of Jouga. Who are they, and are any of the residents safe from their wrath?

Tomboy Ryouko Ookami is a fierce boxer and the assigned bruiser of her club. Of course, no normal high school club needs a bruiser, but the Otogi Bank operates more akin to an actual bank. Here, the students can ask for favors from the club as long as they promise to return the favor in the future. Sixteen-year-old Ryoushi Morino is a shy boy, a far cry from the Otogi Bank members. To his biggest surprise, after unsuccessfully confessing to Ryouko, he inadvertently finds himself joining the club! Ookami-san to Shichinin no Nakama-tachi follows the everyday lives of the Otogi Bank members as they tackle favors that range from the mundane to the dangerous. However, since Ryoushi's sole motivation is to win Ryouko over, she doubts he will be able to have her back in a fight, especially when he can't even stand having people look at him—much less fight anyone!