The Noblesse Cadis Etrama di Raizel, also known as Rai, is enrolled in Ye Ran High School by his servant Frankenstein to stay hidden from the sights of the Union, a mysterious organization out for Rai's blood. Rai commences his life as a student, making himself familiar with his classmates and the daily activities of humans. However, his new life is far from peaceful, and Rai is soon forced to save his new friends from the hands of the Union that had abducted them. Meanwhile, M-21—a Union agent gone rogue during Rai's rescue operation—joins the Ye Ran High School security staff after a proposition by the school's director, who happens to be none other than Frankenstein himself. On the surface, M-21 is a prim and proper employee, but in truth he is shackled by his former ties to the Union and the inevitable consequences of betraying the organization. To further complicate matters, Nobles Regis K. Landegre and Seira J. Loyard enroll in the same school to investigate the Noblesse. While the Union conducts a manhunt for M-21 to extract clues regarding their missing agents, Rai is forced to keep his identity hidden while protecting all that he holds dear.

Picking up where season one left off, Juzo Inui (Gun Slave Unit Device 13) has Rosa's data. Although it seems like everyone wants it, either to expose it or to destroy it, really no one is interested in it. Wachowski, the leader of the anti-Extended terrorist organization Spitzbergen, attempts to coerce Tetsurō to use Harmony to command Juzo to destroy Gun Slave Unit Device 7, who works for Berühren. Juzo does eventually fight Seven, but -- between corruption and double-crosses -- Berühren still pulls all the strings. (Source: ANN)

In the one-of-a-kind samurai-general-reincarnated-as-a-canine comedy, Nobunaga perishes at Honnouji as in history, and reincarnates in modern-day Japan as a dog named Shinamon. Other Warring States era warlords such as Takeda Shingen eventually join him, also as dogs. (Source: ANN)

Natsuza Yuzuki has been playing rugby as a left-winger ever since he was a child. After enrolling in Doushisha University, he quickly becomes a rising star in the Kansai University League. His dreams are shattered, however, when a nasty motorbike accident leaves him with a spinal hernia—making him unable to be able to play rugby ever again. With no role available other than the position of manager, he accepts his new post and hopes his squad can obtain a league title. Yuzuki's team is an unlikely group, including his stoic best friend and full-back Seiichirou Jingyouji; hot-headed first-year Yasunari Tsuru, who harbors a strong dislike for Natsuza, filling his senior's old position as left wing; and Yuu Mashiro, who is struggling to hold his ground as a scrum half. Despite Natsuza putting his all into training his team for a league title, their squad still feels incomplete. A year ago, Ibuki Ueka, the genius fly-half that was once Doushisha's ace, suddenly quit rugby—and now Natsuza is determined to get him back.