A scourge has descended upon vampire society in the form of serial murders. The killings appear unrelated at first glance, but every crime scene has one thing in common: a card left behind, bearing the words True of Vamp—the name given to the legendary progenitor of all vampires. The Vlad Agency, a secret intelligence operation, summons the renowned aristocrat Dali Delico to lead the task force investigating the murders. However, Dali refuses, choosing to focus on raising his children. His old colleagues—Gerhard Fra, Henrique Lorca, and Dino Classico—plead with him to balance his duty to the agency with child-rearing. He agrees on one condition: the other three men must also care for their children during the investigation. Dali's estate therefore becomes a nursery and the base of operations for the four noble vampires. Meanwhile, a criminal organization Dali knows all too well lurks in the shadows with evil intentions that threaten to cause the collapse of the entire vampire society.

Asa and Kame strike up an immediate friendship when they arrive at the same time for their first day of duty at the Ooku, the splendid pleasure palace housing the harem of Lord Tenshi. The two young women are there to join the many hundreds of other maidservants—men are barred from entering, with immediate beheading the price of trespassing. It soon becomes clear that behind the luxurious lifestyle and ritualized routines of the Ooku lie sinister schemes and cynical rivalries. Meanwhile, a mysterious wandering potion-peddler known only as the Medicine Seller subtly insinuates himself into the Ooku, just as an uncanny, otherworldly menace begins to reveal itself. (Source: Fantasia Festival)

Though hesitant, Miyo Saimori decides she is finally ready to attend a party with her fiancé Kiyoka Kudou. She has been practicing the etiquette needed for such an occasion with the help of Kiyoka's sister, Hazuki. At first, Miyo feels pressured by all the attention she receives; however, she eventually grows used to the unfamiliar environment and makes new acquaintances. Through these encounters, Miyo learns more about her family's past and the significance of creating connections with others.

Ayumu Fujino may only be in the fourth grade, but she already basks in high praise for her hand-drawn four-panel comics featured in the school's newspaper. However, when she is asked to share the page with Kyoumoto—a reclusive student she has never met—Fujino feels inadequate for the first time: her free-spirited drawings look embarrassingly amateurish next to Kyoumoto's breathtakingly detailed art. For a year, Fujino shuts out the world, obsessively studying manga creation and drawing tirelessly to catch up to her faceless competition. But Kyoumoto's talent far exceeds hers, and Fujino quits it all. Another year passes, and on the day of their graduation, Fujino finally meets Kyoumoto. This unkempt, shy, and stuttering girl has actually been Fujino's biggest fan all along. Their encounter reignites Fujino's passion for art and sparks the beginning of a years-long friendship built on rivalry, admiration, and their shared love of manga.