Yuusei Fudou is out to get back what was stolen from him. The world of dueling has evolved, with Riding Duels becoming the peak of entertainment for the residents of Neo Domino City. They are played on D-Wheels, a hybrid between Duel Disks and motorbikes. After the mechanically skilled Yuusei managed to build his own D-Wheel, his former friend Jack Atlas stole it alongside Yuusei's best card, Stardust Dragon; ditching their decrepit hometown of Satellite, he escaped to Neo Domino City. In the two years since then, Jack has risen to the top of the dueling world, while Yuusei has been making preparations thanks to the help of his friends. With his new D-Wheel finished, he now sets off to Neo Domino City, his only goal to find Jack. Unbeknownst to either of them, there are far bigger things at stake than they can imagine, with puppeteers pulling the strings behind the scenes.

Anubis, an ancient Egyptian evil that was defeated by Yugi's alter ego centuries ago, has returned to exact revenge. Wielding the power of the Eighth Millennium Item, Anubis is determined to destroy Yugi and take over the world. (Source: ANN)

In the ever-growing world of Duel Monsters, as duelists improve their skills and rise up the ranks, duels become increasingly complex. By adhering to strict rules, in addition to using and learning proven strategies, one can develop into a strong duelist. However, as a boy who loves inventions and discovering new possibilities, elementary school student Yuuga Oudou finds the current way of dueling predictable and rigid—in other words, boring. Thus, he aims to craft a new path in dueling with his exhilarating new invention: Rush Duels. His ambition soon catches the attention of Tatsuhisa Kamijou, a fellow elementary school student, who brings him to a mysterious place in an attempt to discover the potential of the new system. While Yuuga aims to implement Rush Duels as the new dueling standard and overthrow the conventions of the game, he opens the door to his ultimate goal—to make dueling exciting again.

For hearing-impaired university student Yuki Itose, silence has been a natural part of life since birth. Her world is small and isolated; she commutes to campus, interacts with her best friend Rin Fujishiro, and communicates through writing and text messages—a lifestyle that offers little to no change. One day, during her commute, Yuki meets fellow student Itsuomi Nagi, a multilingual travel enthusiast and friend of Rin. When Itsuomi learns of Yuki's condition, he takes it in stride, moving Yuki's heart. From this one simple gesture, Yuki and Itsuomi's lives start changing day by day as they let each other into their own worlds.