From squabbles about groceries against the ambient noise of the TV to their daily shenanigans, the Yamada family invites only a few unusual gazes—similar to any typical household. But despite their prickly exteriors, each of them genuinely cares for one another, making sure to smile and laugh through their otherwise dull and mundane lives. Tonari no Yamada-kun is an intimate and fun look into the lives of a typical Japanese family.

Miyo Sasaki is an energetic high school girl who comes from a broken family consisting of her unconfident father and an overly invested stepmother, whose attempts at connecting with Miyo come across as bothersome. Seeing Kento Hinode as a refuge from all her personal issues, she cannot help herself from forcing her unorthodox demonstrations of love onto her crush. While Miyo is unable to get Kento's attention as herself, she manages to succeed by interacting with him in the form of a white cat, affectionately nicknamed Tarou by Kento. But Miyo soon realizes that she cannot help Kento with the various problems she overhears in her cat form and is now caught between two tough choices. Will she continue her relationship with him as a cat, or will she reveal her identity and risk what they have in order to help him as her human self?

A millennium has passed since the catastrophic nuclear war named the Seven Days of Fire, which destroyed nearly all life on Earth. Humanity now lives in a constant struggle against the treacherous jungle that has evolved in response to the destruction caused by mankind. Filled with poisonous spores and enormous insects, the jungle spreads rapidly across the Earth and threatens to swallow the remnants of the human race. Away from the jungle exists a peaceful farming kingdom known as the Valley of the Wind, whose placement by the sea frees it from the spread of the jungle's deadly toxins. The Valley's charismatic young princess, Nausicaä, finds her tranquil kingdom disturbed when an airship from the kingdom of Tolmekia crashes violently in the Valley. After Nausicaä and the citizens of the Valley find a sinister pulsating object in the wreckage, the Valley is suddenly invaded by the Tolmekian military, who intend to revive a dangerous weapon from the Seven Days of Fire. Now Nausicaä must fight to stop the Tolmekians from plunging the Earth into a cataclysm which humanity could never survive, while also protecting the Valley from the encroaching forces of the toxic jungle.

The main character, a cat named Nyatto, embarks upon a journey to save his sister's soul, which was ripped in two when Nyatto tried to save her from Death. She trails after him, brain-dead. They encounter many brilliant, mind-bending situations, beginning with a disturbing magic show. (Source: ANN)