After an interplanetary war at the beginning of the 21st century, planet Earth has been left in ruins, with much of its ecosystem completely destroyed. Because it was no longer possible to live a normal life on this planet, the inhabitants are forced to move on to other planets where life will, hopefully, be more comfortable. The Deep Galactic Trade Organization, a totalitarian government that affects many of the newly inhabited planets, has somehow come to the conclusion that music is a source of evil, and that it must be banned and destroyed for good. The talent group AKB0048 is soon formed, based on the original AKB48 members that once lived on Earth. Even though their music is now considered universally illegal, they make it their mission to bring their music back to life by travelling from one planet to another and holding as many concerts as they possibly can. They must undergo a whole new set of training methods in order to become the best that they can possibly be, while also avoiding the constant danger of being arrested because of their music. Join interplanetary popstars AKB0048 as they try to save the world－with music!

Sonnet is a cyborg/esper from a harsh background and now trained to be the ultimate warrior and most powerful weapon in the world. She is sent to Japan to watch Komatsuzaki Lan, who is thought to be controlled by the rage of the esper Akai Kiba (Crimson Fang). Lan is a quiet girl who knows she's different from everybody else and starts to show signs of Crimson Fang after coming into contact with Sonnet. In the course of fighting with Lan, Sonnet starts to rediscover her humanity. At the same time Lan has to fight to retain her humanity and control the Crimson Fang. (Source: ANN)

It's sometime in the future and the story starts off with Kei and Ai running for their lives. Ai is a little girl who holds a terrible secret which could destroy the current world. The world is now populated by Headmeters, people who have psychic powers and their strength is shown on their forehead when they fight. However, Kei was an experimental subject and his strength never went above level 5 while other surpasses his ability effortlessly. While escaping, when in desperate moments, Kei could increase his ability to infinity when Ai is in trouble. The one who's after her have a deep secret, aided by a small dwarflike man living in a robotic suit. Eventually Ai is captured and Kei, a sherlock holmes detective and another Headmeter who was converted to the good side when Kei unleashed his horrible powers through Ai must go and rescue her. Together they must save Ai and the secret which she holds. What is the secret of Ai? Who is she? (Source: AniDB)

The OVA adaptation Moe Can Change! is created by Frontier Works, based on a free-to-play game developed by Ambition for mobile phones. The original playful bishoujo Miroid-raising / clothes-changing moe game has the player joining a beta test program for androids, who the player must raise and dress up as girls. (Source: Animekon)