Kudou Shinichi is living his life as Edogawa Conan, but those days seem like they might end pretty soon. The Black Syndicate is coming dangerously close to learning the truth about Shinichi having survived. Conan and everybody around him may end up dead if he doesn't manage to find Irish—a member of the Black Organization who has infiltrated the police forces, currently investigating a big serial murder case.

Four childhood friends are in their second year at Homare High School: kind and cheerful Shun Matsuoka, hot-tempered Kaname Tsukahara, and the Asaba twins, gentle Yuuta and lazy Yuuki. When a dynamic transfer student, Chizuru Tachibana, joins their group, the friends get caught up in his creative yet troublesome ideas that end up bringing excitement to their everyday lives. With new encounters and experiences, they begin to learn more about each other and themselves.

Magano, a parallel realm filled with monsters known as Kegare, is a place where exorcists deal with all impurities. Benio Adashino is a prodigy exorcist who is recognized for her strength and is summoned to Tokyo by the Exorcist Union. On her way, she plummets into the arms of Rokuro Enmadou, a young exorcist with a troubled past. But the impurities of Magano do not rest. When these two exorcists witness a couple of children stolen by a Kegare, Benio rushes to save them, dragging Rokuro along with her into Magano. Engaged in a fight she is on the verge of being defeated in, Benio is saved by Rokuro, revealing himself capable of being her rival in talent. Sousei no Onmyouji tells the story of two talented exorcists who are destined to become the Twin Star Exorcists and the prophesised parents of the Miko—the reincarnation of Abe no Seimei—who will cleanse the world of all impurities.

High school biology teacher Tetsuo Takahashi may look like your average everyday instructor, but beneath his gentle appearance lies something less ordinary: his fascination for the Ajin, more commonly known as Demi. Although these half-human, half-monster beings have integrated into human society, Takahashi believes that much about them will remain unknown unless he interacts with them firsthand. Demi-chan wa Kataritai follows Takahashi's daily life in Shibasaki High School together with his three Demi students—Hikari Takanashi, an energetic vampire; Kyouko Machi, a gentle dullahan; and Yuki Kusakabe, the shy snow woman. Along the way, Takahashi also meets fellow teacher Sakie Satou, a succubus with an aversion towards men. To fulfill his goal of learning more about the Demi, Takahashi decides to conduct casual interviews with the girls to learn more about their abilities, psyche, and interaction with human society. As Takahashi strengthens his bond with his students, he soon discovers that the Demi are not as unusual as he initially believed.