Natsume Yuujinchou San follows Takashi Natsume, a boy who is able to see youkai. Natsume and his bodyguard Madara, nicknamed Nyanko-sensei, continue on their quest to release youkai from their contracts in the Book of Friends. Natsume comes to terms with his ability to see youkai and stops thinking of it as a curse. As he spends more time with his human and youkai friends, he realizes how much he values them both and decides he doesn't have to choose between the spirit and human worlds to be happy.

Rimuru Tempest is victorious following his climactic showdown with Demon Lord Clayman. With Diablo's aid, the war with the Falmuth Kingdom ends decisively in Rimuru's favor. Fueled by increased migration and the integration of Jura Forest, the nation of Tempest undergoes rapid growth. Rimuru's victory shifts the balance of power, giving rise to a renewed period of peace—but whether that peace will last is another matter. Yuuki Kagurazaka and Kazalim are conspiring with the Harlequin Alliance to bring about Rimuru's downfall. Furthermore, the Western Holy Church continues its intolerant crusade against Rimuru and his non-human subordinates. Both allies and enemies engage in a battle of wits, carefully advancing their agendas without shattering the delicate status quo. But once the first domino inevitably falls, the race to supremacy begins.

As Mikado Ryuugamine continues to purge the Dollars from within in accordance with his warped sense of justice, Masaomi Kida hopes to bring his friend back to his senses by bringing the Yellow Scarves together once more. Little do they know that a far more dominant force is about to enter their struggle for power, one that their friend Anri Sonohara is all too familiar with. Meanwhile, the group that has gathered at Shinra Kishitani's apartment realizes that they are on the brink of something life-changing, an event that will throw Ikebukuro into a spiral of confusion. Their anxiety is realized when reports of Celty's head being found in public start to appear all over the news as Kasane Kujiragi begins to make her move. Gone are the brief periods of tranquility as the current turmoil sets the stage for one final performance in this thrilling conclusion to the story of Ikebukuro's finest.

For Kanade Amakusa, life as a high schooler should have been normal, and it would have been—if he wasn't living with the most ridiculous curse imaginable. Absolute Choice, a system forced upon him by a self-proclaimed god, randomly presents a mental selection of actions that he must act out based on his choice. To add to his dilemma, it tends to occur in the most public of places, and his options never seem to deviate from the rude and crude in nature. As a result, the helpless boy stresses through each day, fumbling to repair his already tarnished reputation while desperately praying to avoid the next spontaneous episode of Absolute Choice. To his dismay, the one in charge is always one step ahead of him and proceeds to not-so-subtly choice him into the lives of several girls at his school. Just when Kanade's school life can't seem to be doomed any further, a decision that he reluctantly selects on the way home sends a beautiful girl crashing down from the sky, along with the promise of more hysterically hellish choices.