Summer is in full swing, and so is the love between Sawako Kuronuma and Shouta Kazehaya. From attending summer school together to meeting each other's parents, the two enjoy quality time together while tackling the feelings of self-doubt and emotional strain that come with their newfound love. Meanwhile, Sawako's close friends, Chizuru Yoshida and Ayane Yano, struggle through their own romantic dilemmas as their past experiences with relationships clash with their present feelings. Full of inner turmoil, the youngsters' desire for intimacy persists through their second year of high school as they weave through the labyrinth of indecision and insecurity that is love.

In future Japan, in a time when android housekeepers have become commonplace, society strictly abides by the Three Laws of Robotics, which all androids must follow. Under the influence of the Robot Ethics Committee, androids are treated the same way as lesser technology, such as household appliances. However, a minority with an adoration for androids exists, categorized as android-holics, and are shunned by the general public. Rikuo Sakisaka was raised to accept society's precept about androids, and is perfectly aware that they are not human. That is, until the day he discovers a strange message buried within the activity logs of his household android, Sammy. This leads him to Eve no Jikan, a cafe with only one rule that its patrons must adhere to: there must be no distinction made between humans and androids. Curiosity drives Rikuo to learn more about the shop, and he attempts to unearth the reason behind Sammy's peculiar behavior.

Brandon Heat and Harry MacDowel, two friends so close they could be called brothers, receive an abrupt and violent reminder one fateful day of how appallingly merciless the world around them can be. Their whole lives before then were simple and easygoing, consisting largely of local brawls, seducing women, and committing petty theft to make a living and pass the time. What they failed to realize is that in this cruel world, happiness is fleeting, and change is inevitable. Enter Millennion, the largest and most infamous mafia syndicate in the area, which accepts Brandon and Harry into their ranks and starts them at the bottom of the food chain. Harry has ambitions to ascend the ranks and one day replace Big Daddy as the supreme leader of Millennion, while Brandon only wishes to support his friend and appease Big Daddy who has taken custody of the woman Brandon loves. Based off the third-person shooter video game under the same name, Gungrave is an epic story of friendship, betrayal, and avarice that spans the course of several years, ultimately tying back to the gripping and foreboding first episode, all the while building up to the story's thrilling conclusion.

Deep in the forest, far from any human contact, there lives a child named Ryouma Takebayashi. He engages in the rather strange hobby of keeping various types of slimes as pets. Furthermore, despite his young age, he has a sturdy physique and good compatibility for magic. All of this is because, having endured much hardship in his previous life, three gods grace Ryouma with a second chance to pursue one goal: savor the wonders of life. After three years of comfortable solitude pass by, Ryouma meets people that will change his current life forever. When he encounters and helps some soldiers tend to their wounded comrade, the group convinces him to accompany them to visit the nearby town's ducal family. Ryouma agrees and soon embarks on a journey to explore the vast world beyond his home.