After passing away, a Japanese office worker finds himself reincarnated in another world as Ars, the newborn son of the noble Louvent family. The Summerforth Empire, where the Louvents rule over a small territory of a few thousand people, is a medieval-like land plagued by social inequality and political instability. As Ars grows older and learns more and more about his new environment, he becomes convinced that war will soon erupt. Fortunately, though Ars was not blessed with unrivaled strength or extraordinary magical aptitude, he does possess Appraisal: a seemingly unique skill that allows him to instantly grasp someone's current abilities and latent talents merely by looking at them. In an effort to prepare his domain for the imminent strife, Ars resolves to enlist the most exceptional people he can find, paying no attention to superficial qualities like race or social status.

To the casual eye, the amnesiac bounty hunter Wu Liuqi looks quite intimidating. With his deadly telekinetic scissor techniques and his ability to seamlessly transform into anything, one would not expect his modest demeanor. In fact, Wu is quite terrible at his job. Often times the freelancer can be found botching an assassination or targeting the wrong person. While his failures could be due to his subpar skills, it usually boils down to him being a normal kid, with a heart unsuited for his line of work. Accompanied by his feathered friend Dai Bo, Wu is on a simple quest to regain his memories. Although his inconspicuous day job as a hairdresser and his after-hours occupation are simply a means for him to repay debt, his various ventures seem to intertwine with his pursuit to recover his lost past.

The world of Yozakura Quartet is actually not one, but two worlds: one of humans, and one of youkai. Despite appearing mostly human, youkai may have animal like physical traits, along with a number of special abilities. Normally youkai are confined to their world, but some have found their way into the realm of humanity. As a symbol of peace, and a bridge between the two realms, a city was constructed within the protective barrier of seven magical trees, otherwise known as the Seven Pillars. This city of Sakurashin is home to both humans and youkai, with the peace between them maintained by the Hizumi Life Counseling Office. The director of this office is Akina Hiizumi, a teenager with the inherited family ability to perform “tuning,” which can send harmful youkai back to their world permanently. He is aided by a group of girls, including the town’s 16 year old youkai mayor, Hime Yarizakura, their town’s announcer and resident telepath, Ao Nanami, and Kotoha Isone, a half-youkai who can summon objects just by stating the object’s name. As new residents enter and mysterious events begin to take place, this quartet of protectors and their closest friends must continue to guard the city of Sakurashin, and maintain the fragile balance of peace between humans and youkai.

Ichirou Kuga has suddenly found himself taking on the responsibility of caring for his two younger siblings after their father's untimely death. To make ends meet, Ichirou rents out rooms in the apartment complex he inherited and works full-time as a shoujo manga artist. However, his manga sales are low, his assistants have recently left, and deadlines are fast approaching. As stress threatens to overtake Ichirou, salvation comes in the form of an extremely competent novice artist, Shiori Goshiki, who becomes his new assistant. With her skills, they are able to tide over the difficult situation, and things begin looking up. But in a bizarre accident, a supernatural experience unfolds between Ichirou and Shirou, which leads her to declare them engaged. With this seemingly innocuous action upending his life, Ichirou now has to manage his new and peculiar relationship with the mysterious girl, all the while following his own passion and fulfilling the duties that rest on his shoulders.