According to legend, Beelzebub, one of the seven princes of Hell, betrayed God and was banished from Heaven for eternity. Beelzebub now leads the kingdom of Pandemonium, where all former angels roam and work every single day of their immortal lives. A devil like him would give people chills at the mere mention of his name. But what if Beelzebub is not as evil as initially thought? What if he was obsessed with fluffy things? And what if Beelzebub is actually a woman? That is what new assistant Myurin discovers when he is hired to serve Her Majesty Beelzebub. She may know exactly what to do to keep Pandemonium running like clockwork, but whenever she leaves the professionalism of the office, the girl needs some assistance in order to function like a normal... devil. As much as Myurin can't stand being unprofessional, he is secretly obsessed with her adorable antics, and his new job teaches him that everything is not exactly what it seems, especially with the other head devils of Pandemonium.

At only 12 years old, Takumi Harada is already hailed as a prodigious baseball pitcher. But when his family moves to the backwater town of Nitta, Takumi has no choice but to join his new school's unskilled baseball team. This development has little effect on the boy, as he believes it is more interesting if this no-name club becomes a powerhouse due to his presence. However, due to his overwhelming talent, Takumi is in need of a catcher able to keep up with his pitches. His worries are soon put to rest after meeting Gou Nagakura. As his fan and fellow student, Gou is eager to prove that he is not a simple braggart, but rather a player skillful enough to catch Takumi's pitches. Amid struggling to form a battery with Gou, Takumi comes into conflict with his new teammates due to his irreverent personality but grapples to find the true joy of the sport under his grandfather's guidance.

Fleeing a traumatic childhood, lone mercenary Guts drifts from battle to battle, striking down powerful enemies with his unwieldy sword. After one skirmish, Guts clashes with the mystifying Griffith and his small army known as the Band of the Hawk. The victorious Griffith drafts Guts into his ranks, granting the swordsman a kinship unlike anything he has ever known. Alongside the skilled warrior Casca, Guts helps Griffith guide the band to fame and glory. But as he gains military prestige, Griffith becomes the target of assassination attempts and political schemes. He uses Guts to further his ambitious rise to power, taking advantage of the swordsman's lack of aspiration. Even as he grows closer to Casca, Guts' absence of direction robs him of any sense of belonging. Fostering opposing desires, Guts and Casca fight for Griffith's dream—although fractures forming among the trio threaten to disrupt their world.

The day before her birthday, Akane is asked to retrieve her birthday present from her aunt Chi's shop. While looking around, she chances upon a mysterious slab with a hand-shaped cavity in it. Curious, she places her hand in it, and—to her surprise—it fits perfectly. The next thing she knows, a strange alchemist named Hippocrates and his apprentice Pipo appear, calling Akane the legendary Goddess of the Green Wind. The two eccentrics claim to be from a different world connected to the shop's basement. With the peace of their world in jeopardy, Hippocrates and Pipo seek the help of the only one capable of saving it from destruction: Akane. Forced to accompany them on a journey to restore the land's harmony, Akane—with her aunt in tow—sets off to discover a magical new place.