Self-professed home security guard Mahiro Oyama has not left his home in years, secluding himself in his room playing erotic visual novels. This depraved lifestyle causes his prodigious sister, Mihari, to worry about his well-being. In hopes of solving this problem, she devises a plan to rehabilitate him back to normalcy. The first part of Mihari's plan is to concoct a medicine that changes her brother's biological constitution into a bona fide female, much to Mahiro's vehement dismay. Stuck in this predicament, Mahiro has no choice but to live out his life as a cute girl until the effect wears off—if it ever does.

Amatsuyu Jouro Kisaragi is a completely average second-year high school student who has two dates over one weekend⁠—with the student council president Sakura Cosmos Akino on Saturday, then with his childhood friend Aoi Himawari Hinata on Sunday. Sadly for Jouro, both girls proclaim their love for his best friend Taiyou Sun-chan Ooga, the ace of the baseball team. Accepting each of their requests for advice and guidance, he is now responsible for helping the two girls win the heart of the same guy. Unbeknownst to his friends, Jouro's friendly and obtuse image is all but a ruse designed to cast himself as the clueless protagonist of a textbook romantic comedy. A schemer under his cheery facade, he makes the best of this unexpected turn of events with a new plan: get Sun-chan to fall for either Cosmos or Himawari and take the other as his own prize. But Jouro's last-ditch effort is threatened by the gloomy, four-eyed Sumireko Pansy Sanshokuin, who surprises Jouro with not only her knowledge of his secret personality but also a confession to the true self he hid for all this time. Stuck in this hilariously messy situation, each of the five students must navigate countless lies, traps, and misunderstandings to come out on top.

According to the theories of oneiromancy, dreams of dragons represent the struggle of losing yourself to your own anger. Fittingly, Souya Kuroi wakes up from a nightmare of a massive dragon destroying everything around him in a blaze of rainbow colored light. After being told that he lost his parents and memory in a strange accident, the waking world becomes another nightmare in itself. With this dream being his only memory, he has no choice but to be taken care of by his two strange guardians: the spunky and energetic maid Ginko, and a huge cat known only as Sensei. His new life is turned upside down when the denizens of Saromisaka City are beset by a teddy bear-shaped UFO. When military power proves to be ineffective, seven mysterious people rise up to fight off the monstrosity. These heroes destroy the invader in a flurry of rainbow colored lights, the very same lights that Souya saw in his nightmare. With the alien threat repelled, these seven strangers find themselves facing a new adversary: Souya. Swearing vengeance upon the people who decimated his old life, he begins his crusade against these heroes and becomes embroiled in a struggle of galactic proportions.

Ever since he lost his family in an explosion, Mirai Kakehashi has lived a life of pain and despair. Every day, he endures abuse at the hands of the relatives who took him in. As his anguish steadily chips away at his will to live, he is eventually pushed to the brink. Prepared to throw it all away, he stands on the edge of a precipice and takes the leap. However, instead of falling to his death, he enters a trance where he meets a winged being who claims to be his guardian angel. Named Nasse, the angel offers him two priceless abilities and convinces him to go on living. When Mirai experiences the marvel of his new powers firsthand, he gets a taste of the freedom that was locked away from him for so long. Armed with Nasse's gifts, Mirai is flung into a showdown with 12 other individuals, one of which will be chosen to become the next God. In stark contrast to when he wanted to end his life, Mirai is now prepared to do whatever it takes to protect his bleak chance at happiness, lest it be wrenched from his grasp forever.