Despite being burdened with crippling debt to the morose Haruitsuki Abeno, Hanae Ashiya has come to enjoy his job as an exorcist. His ability to communicate with youkai has given him a sense of responsibility regarding the magical creatures, and he continues to work hard to send them to their true home in the Underworld. As Ashiya’s life finally stabilizes, the youkai threaten to upset it once again. Knowledge of his existence has begun to spread, and not everyone is happy to have a human working for the Mononokean, the interdimensional tea room. But one day, a simple visit to the Underworld draws the attention of those in power, and Ashiya soon learns that not every youkai is willing to go along with Abeno's plans.

Based on the horror novel by Fujio (A) Fujiko.

Edward Elric, a young, brilliant alchemist, has lost much in his twelve-year life: when he and his brother Alphonse try to resurrect their dead mother through the forbidden act of human transmutation, Edward loses his brother as well as two of his limbs. With his supreme alchemy skills, Edward binds Alphonse's soul to a large suit of armor. A year later, Edward, now promoted to the fullmetal alchemist of the state, embarks on a journey with his younger brother to obtain the Philosopher's Stone. The fabled mythical object is rumored to be capable of amplifying an alchemist's abilities by leaps and bounds, thus allowing them to override the fundamental law of alchemy: to gain something, an alchemist must sacrifice something of equal value. Edward hopes to draw into the military's resources to find the fabled stone and restore his and Alphonse's bodies to normal. However, the Elric brothers soon discover that there is more to the legendary stone than meets the eye, as they are led to the epicenter of a far darker battle than they could have ever imagined.

After overcoming various tumultuous events, mercenary sergeant Sousuke Sagara of Mithril and Whispered school girl Kaname Chidori return to their normal high school lives. Sousuke continues his efforts to assimilate with the civilian population and manage his mission at the same time, while Kaname attempts to support his endeavors (even though his antics often drive her up a wall). However, as their lives calm, new problems begin to appear. The appearance of an independent terrorist organization known as Amalgam and internal conflicts within Mithril threaten to wreak unity into a series of failures and betrayals. And new, powerful Arm Slave models only worsen the situation when the world's peace is at stake. As Kaname and Sousuke face their own inner battles amidst life-threatening fights, will they be able to make the right choices and change their future?