Fourth season of Strike the Blood.

In the year 2020, a nation faces the pervasive threat of the Others—mysterious monsters who fall from the sky and feed on human brains. At the same time, psionics, a hormone that gives certain people extrasensory abilities that are effective against the Others, is discovered in the human body. Subsequently, the nation's founder establishes the Other Suppression Force (OSF) to combat these monsters and save humanity. Commonly referred to as the Scarlet Guardians, young individuals with psionics undergo intensive training to join this group. One day, the nation prepares an induction ceremony for the exceptional recruits who completed the grueling training to become Scarlet Guardians. Among these young elites is Yuito Sumeragi, the determined son of the nation's founder; at the age of five, he was rescued by a woman in the OSF. To repay this debt, he joins the organization, eager to put his training to good use. As he meets his new comrades, he faces a big problem—the woman who saved him years ago closely resembles one of his teammates. However, this should be the least of his worries—unbeknownst to him, a conspiracy is brewing, one with the capability to shake the entire country.

A new tournament, Squad Jam 3, has been announced in the popular VR game Gun Gale Online. This time, Pitohui, one of the best performers in the previous competition, offers to team up with Karen Kohiruimaki, better known in-game as LLENN, the Pink Devil. Despite her initial reluctance, Karen agrees to join Pitohui's team, LPFM, since she looks forward to facing SHINC, her rivals from the previous Squad Jam. The newly formed LPFM enrolls in the tournament and is quickly recognized as the favorite to win due to the caliber of its players. As they strive to come out on top and win Squad Jam 3, LLENN, Pitohui, and the other members of LPFM battle against other competitors and tackle unexpected challenges.

In a world where academic success decides your entire future, the exam room becomes a ruthless battlefield. Passing the exams guarantees a successful future. Failing dooms you to live a cruel life, tormented by suffering and despair. Only the most intelligent—or cunning—students make it out alive. These are the two strategies of combat: spend your entire life studying for the test, or perfect your cheating strategy. The students who dedicate themselves to studying are called “Learning Type” students, and they are forced to collaborate with a “Cheating Type” student in order to battle their rivals for the top grades. The cheater Zhuge Mu Ming and studious academic Qiao Yi Huang decide to team up against the exams. However, the allies are soon divided, becoming bitter rivals. Will they be able to make it on their own? And if so, who will survive the challenge and emerge victorious?