Taro Sado is a high school student who lives his day to day life with a big secret—he's a masochist! Encouraged by his cross-dressing best friend Tatsukichi Hayama, Taro asks the Second Voluntary Club for help with his problem and ends up joining the club after they vow to fix him. However, it turns out that all of the members of the club have some serious issues. The club leader Mio Isurugi is a self-designated god who is afraid of cats, Arashiko Yuuno has a severe fear of men, and the club advisor Michiru Onigawara is a sadist who enjoys making people cosplay. Together with other wacky characters such as Yumi Mamiya, a talented masseuse and Yuuno's best friend, and Noa Hiiragi, the president of the invention club, they all learn about the importance of acceptance and kindness.

The Tsunashi couple is as lively and offbeat as ever. Hardcore otaku shut-in Hajime and workaholic office lady Kaoru still get themselves into hilarious situations thanks to both their own eccentric natures and the bizarre group of friends surrounding them. After learning about Kaoru's pregnancy, Hajime works harder than ever to become a good husband and a worthy father. Meanwhile, Kaoru reflects on their relationship and remembers all of the trials and tribulations that brought them closer. The two of them continue to put their best foot forward in their lives and their marriage—all for the sake of long-lasting, selfless love.

Suehara Maru is childhood best friends with one of Hozumino High School's most popular girls, Kuroha Shida. Cute, outgoing, and affectionate, Kuroha is the perfect older sister type. She has boys constantly begging at her feet to be with her. Yet, when she confesses to Suehara one day, he immediately rejects her; he just can't think of her in that way! Besides, he already has his sights set on his first love—school idol and renowned author Shirokusa Kachi. Suehara believes that he has a chance with Kachi after one fateful meeting, but soon, he finds out that Kachi has a boyfriend! With his dreams now shattered, Suehara agonizes over what could have been. That is, until Kuroha approaches him with a proposal: let's get revenge.

Natsume Yuujinchou San follows Takashi Natsume, a boy who is able to see youkai. Natsume and his bodyguard Madara, nicknamed Nyanko-sensei, continue on their quest to release youkai from their contracts in the Book of Friends. Natsume comes to terms with his ability to see youkai and stops thinking of it as a curse. As he spends more time with his human and youkai friends, he realizes how much he values them both and decides he doesn't have to choose between the spirit and human worlds to be happy.