Takao Kasuga, a high school student fascinated by poetry, reveres Charles Baudelaire and even decorates his room with the poet's portrait. On a normal day, Takao forgets his copy of The Flowers of Evil in the classroom. When returning to retrieve it, he steals the sports garments of Nanako Saeki—a model student who Takao calls his muse and a femme fatale. Deeply ashamed of his act which he sees as a sin and what others see as a crime, Takao realizes with horror that Sawa Nakamura, his classmate and social outcast, knows about his theft. Blackmailed by her, Takao is now forced to partake in Sawa's disturbing fantasies, lest she reveals his deeds to everyone. Caught in a negative spiral of increasingly traumatic experiences, will Takao be able to break free from Sawa's thorns and atone for his sins?

Gugure! Kokkuri-san is an eccentric comedy centered around the self-proclaimed doll, Kohina Ichimatsu. Her uneventful life goes from plain to absurd when she summons a fox spirit by the name of Kokkuri-san. But contrary to popular belief, he is not the omniscient, answer-granting spirit from the legend anymore. The loss of believers in modern society has rendered him powerless. Upon meeting the bizarre girl who summoned him, Kokkuri-san is shocked to discover that Kohina not only lives alone, but survives on just cup ramen! Filled with concern for the young girl, he takes it upon himself to ensure that Kohina has proper meals and lives a decent life. Thus begin Kokkuri-san's less-than-hopeful endeavors and their peculiar life together.

Upon hearing news that his mother was on verge of death, Haru Kaidou—the eldest son of the family—flies all the way to Canada. The moment he arrives, he learns that not only did his mother fool him, but he is also supposed to take care of his adoptive brother, Ren Kaidou, an antisocial kid who feels more comfortable around dogs than people. Due to his new brother's distrustful nature, Haru initially has a hard time reaching out to Ren but their relationship eventually grows. He makes a promise to Ren: they will live together in Japan after Haru graduates from high school. However, due to an unfortunate accident, Haru loses all memories of the summer they spent together, including the promise he made. Five years later, expecting Haru to keep his promise, Ren arrives in Tokyo; but to Haru, Ren is just a random boy claiming to be his brother.

At Fujisaki Girls Academy, student council president Natsuo Maki is the epitome of grace and perfection, admired by all the young girls who attend the school. One day, Riko Kurahashi walks into the student council room on an errand, only to discover Natsuo practicing her kissing techniques on a pillow, an act that is neither graceful nor elegant. Riko soon discovers that Natsuo desires more romance in her life, leading her to practice romantic situations in secret. Sympathizing with her, Riko agrees to help Natsuo with her love research. Named Love Lab, the project practices the essentials of love and romance, such as bumping into each other accidentally and holding hands. Soon, the entire student council joins in on the fun in the Love Lab too! Through their research and real life encounters, what will they learn about romance? Weaving together funny characters and comedic situations, Love Lab builds a story of friendship and romance, while never missing a beat with the laughter.