At the Battle of Sekigahara in 1600, Toyohisa Shimazu is the rearguard for his retreating troops, and is critically wounded when he suddenly finds himself in a modern, gleaming white hallway. Faced with only a stoic man named Murasaki and hundreds of doors on both sides, Toyohisa is pulled into the nearest door and into a world completely unlike his own. The strange land is populated by all manner of fantastical creatures, as well as warriors from different eras of Toyohisa's world who were thought to be dead. Quickly befriending the infamous warlord Nobunaga Oda and the ancient archer Yoichi Suketaka Nasu, Toyohisa learns of the political unrest tearing through the continent. Furthermore, they have been summoned as Drifters to fight against the Ends, people who are responsible for the creation of the Orte Empire and are trying to annihilate the Drifters. As the Ends grow more powerful, so does the Empire's persecution of elves and other demihumans. It is up to Toyohisa and his group of unconventional heroes to battle in a brand-new world war to help the Empire's subjects, while challenging the Ends protecting the land to claim it for themselves.

In the small village of Hinamizawa, Rika Furude and her friends live together in relative harmony. Beneath this mask of peace, however, lies a hidden darkness, one that Rika understands all too well. In this eternal summer, she has been witness to unspeakable horrors. Every time the clock resets, Rika must try to find the villain behind these senseless deaths before tragedy strikes again. However, trying to decipher a mystery when only half the clues are present proves time and again to be disastrous, and each time she believes that things will change, she inevitably fails. As the annual festival approaches, Rika begins her descent from hope to despair in her struggle to break the chains of fate entangling them all.

Isabella, the daughter of the noble York family, is enrolled in an all-girls academy to be groomed into a dame worthy of nobility. However, she has given up on her future, seeing the prestigious school as nothing more than a prison from the outside world. Her family notices her struggling in her lessons and decides to hire Violet Evergarden to personally tutor her under the guise of a handmaiden. At first, Isabella treats Violet coldly. Violet seems to be able to do everything perfectly, leading Isabella to assume that she was born with a silver spoon. After some time together, Isabella begins to realize that Violet has had her own struggles and starts to open up to her. Isabella soon reveals that she has lost contact with her beloved younger sister, Taylor Bartlett, whom she yearns to see again. Having experienced the power of words through her past clientele, Violet asks if Isabella wishes to write a letter to Taylor. Will Violet be able to help Isabella convey her feelings to her long-lost sister?

Yuugi Mutou is a naïve and lonely high school student who is fascinated by games. While staying with his grandfather, the owner of a game shop, he comes across an ancient Egyption relic known as the Millennium Puzzle. Rumored to grant any wish to those who solve the Puzzle, Yuugi becomes determined to solve it to wish for some friends. After years of struggling, Yuugi manages to complete the puzzle and mysteriously finds that his wish has been fulfilled. Meanwhile, a new card game known as Duel Monsters starts rising in popularity. In this game, players called duelists fight against each other with monsters by using magic and trap cards to foil their opponent's plans. Yuugi quickly becomes skilled at the game and lives a peaceful life with his newfound friends. However, Yuugi's peace is short-lived. The undefeated duelist and egocentric billionaire Seto Kaiba suddenly abducts Yuugi's grandfather, forcing him to duel against the rare Blue Eyes White Dragon'' card. Yuugi is thrown into a new world of fierce battles and the stakes continue to rise as dark forces interfere from the shadows. After unexpectedly defeating Kaiba with the help of his other self—the spirit of a nameless pharaoh—contained in the puzzle, he unofficially becomes the top duelist known as The King of Games. However, this new title will attract covetousness and Yuugi will have to use all his intelligence and willpower in order to protect what he holds the dearest to him.