After a horrific alchemy experiment goes wrong in the Elric household, brothers Edward and Alphonse are left in a catastrophic new reality. Ignoring the alchemical principle banning human transmutation, the boys attempted to bring their recently deceased mother back to life. Instead, they suffered brutal personal loss: Alphonse's body disintegrated while Edward lost a leg and then sacrificed an arm to keep Alphonse's soul in the physical realm by binding it to a hulking suit of armor. The brothers are rescued by their neighbor Pinako Rockbell and her granddaughter Winry. Known as a bio-mechanical engineering prodigy, Winry creates prosthetic limbs for Edward by utilizing automail, a tough, versatile metal used in robots and combat armor. After years of training, the Elric brothers set off on a quest to restore their bodies by locating the Philosopher's Stone—a powerful gem that allows an alchemist to defy the traditional laws of Equivalent Exchange. As Edward becomes an infamous alchemist and gains the nickname Fullmetal, the boys' journey embroils them in a growing conspiracy that threatens the fate of the world.

Barely surviving in a barrel after passing through a terrible whirlpool at sea, carefree Monkey D. Luffy ends up aboard a ship under attack by fearsome pirates. Despite being a naive-looking teenager, he is not to be underestimated. Unmatched in battle, Luffy is a pirate himself who resolutely pursues the coveted One Piece treasure and the King of the Pirates title that comes with it. The late King of the Pirates, Gol D. Roger, stirred up the world before his death by disclosing the whereabouts of his hoard of riches and daring everyone to obtain it. Ever since then, countless powerful pirates have sailed dangerous seas for the prized One Piece only to never return. Although Luffy lacks a crew and a proper ship, he is endowed with a superhuman ability and an unbreakable spirit that make him not only a formidable adversary but also an inspiration to many. As he faces numerous challenges with a big smile on his face, Luffy gathers one-of-a-kind companions to join him in his ambitious endeavor, together embracing perils and wonders on their once-in-a-lifetime adventure.

After five years of harboring unspoken feelings, high-schooler Taiju Ooki is finally ready to confess his love to Yuzuriha Ogawa. Just when Taiju begins his confession however, a blinding green light strikes the Earth and petrifies mankind around the world—turning every single human into stone. Several millennia later, Taiju awakens to find the modern world completely nonexistent, as nature has flourished in the years humanity stood still. Among a stone world of statues, Taiju encounters one other living human: his science-loving friend Senkuu, who has been active for a few months. Taiju learns that Senkuu has developed a grand scheme—to launch the complete revival of civilization with science. Taiju's brawn and Senkuu's brains combine to forge a formidable partnership, and they soon uncover a method to revive those petrified. However, Senkuu's master plan is threatened when his ideologies are challenged by those who awaken. All the while, the reason for mankind's petrification remains unknown.

In the distant future, humanity has been driven to near-extinction by giant beasts known as Klaxosaurs, forcing the surviving humans to take refuge in massive fortress cities called Plantations. Children raised here are trained to pilot giant mechas known as FranXX—the only weapons known to be effective against the Klaxosaurs—in boy-girl pairs. Bred for the sole purpose of piloting these machines, these children know nothing of the outside world and are only able to prove their existence by defending their race. Hiro, an aspiring FranXX pilot, has lost his motivation and self-confidence after failing an aptitude test. Skipping out on his class' graduation ceremony, Hiro retreats to a forest lake, where he encounters a mysterious girl with two horns growing out of her head. She introduces herself by her codename Zero Two, which is known to belong to an infamous FranXX pilot known as the Partner Killer. Before Hiro can digest the encounter, the Plantation is rocked by a sudden Klaxosaur attack. Zero Two engages the creature in her FranXX, but it is heavily damaged in the skirmish and crashes near Hiro. Finding her partner dead, Zero Two invites Hiro to pilot the mecha with her, and the duo easily defeats the Klaxosaur in the ensuing fight. With a new partner by his side, Hiro has been given a chance at redemption for his past failures, but at what cost?