Waking up cold and alone in the woods, a nameless man is surrounded by unfamiliar scenes. Without any memories, he is utterly lost until he stumbles upon Kuon—a young girl with animal ears and a tail. She saves him, leading him back to her town while protecting them both from boro-gigiri—giant centipede-like creatures—and a mysterious red slime. After they arrive, she names him Haku after a prominent historical figure from the area. He quickly realizes he is one of a kind—the only one without animal ears and a tail. The two journey to the capital of Yamato, the country in which Kuon lives, meeting more people and making new friends, all the while unknowingly delving deeper into the politics and inner conflicts of Yamato... Utawarerumono: Itsuwari no Kamen follows Haku as he slowly uncovers the secrets of this alien world. He works to solve the mysteries surrounding the red slimes, as well as to stop war from erupting among the nearby countries.

In a war against four overpowered races—angels, demons, undeads, and humanoid beasts—humanity could only prevail thanks to its champion Sid, who defeated the other races' champions and sealed away their armies in four pyramids. In an age where Sid's existence has become but a legend of the past, Kai Sakura Vento is one of the many conscripts tasked with monitoring the pyramids in fear that these old foes would escape. On a peaceful day while spending time with his friend Jeanne E. Anise, the world is suddenly overwritten, transporting Kai to an alternate reality where humanity has nearly been annihilated by the demons and forced into hiding. To make matters worse, his very existence has been erased from this world; all of his friends, including Jeanne, who leads the local resistance efforts in this world, have forgotten about him. Trying to investigate the remains of his former world, Kai encounters Rinne, an enigmatic young woman trapped in a pyramid. Mysteriously inheriting Sid's legendary sword Codeholder, Kai manages to free Rinne from her imprisonment. Determined to fix this reality, Kai joins forces with Rinne and Jeanne to free humanity from demonic rule. But if the valiant soldier wants to have a chance at returning to his original world, he will first have to uncover the cause behind the mysterious alteration of reality.

Rygart Arrow is different compared to the other people in the continent of Cruzon: he is unable to control quartz, branded an un-sorcerer. Despite this, he still befriends the future king and queen of Krisna—Hodr and Sigyn—as well as Zess, the younger brother of the Athens Commonwealth's Secretary of War. Several years later, Rygart discovers that there is a war brewing between Krisna and Athens. While visiting Binonten, the capital city of Krisna, he learns that his misfortune as an un-sorcerer enables him to pilot an ancient Golem, a unique ability that quartz-wielding users lack. As Zess leads one of the Athenian strikes upon the capital, Rygart joins the battle with his newfound power in hopes of mending the schism between the two nations.

Nanoha Takamachi, an ordinary third-grader who enjoys spending time with her family and friends, rescues an injured ferret that she had dreamed about the night before. The next day, the ferret cries out to her telepathically, asking Nanoha to save him. The ferret reveals himself to be Yuuno Scrya, a mage from another world who is trying to collect the dangerous 21 Jewel Seeds that he accidentally scattered across the world. He enlists Nanoha's help, gifting her the magical wand Raising Heart, and teaches her how to become a powerful mage. Days later, after reclaiming a few of the Jewel Seeds, another mage appears: Fate Testarossa. Stronger than Nanoha, Fate refuses to divulge her reasons in trying to collect the Jewel Seeds. Nanoha senses a melancholy in her eyes, but Fate refuses to communicate. Directed by Akiyuki Shinbo, Mahou Shoujo Lyrical Nanoha is a story about the clash of emotions when goals collide.