Hunters devote themselves to accomplishing hazardous tasks, all from traversing the world's uncharted territories to locating rare items and monsters. Before becoming a Hunter, one must pass the Hunter Examination—a high-risk selection process in which most applicants end up handicapped or worse, deceased. Ambitious participants who challenge the notorious exam carry their own reason. What drives 12-year-old Gon Freecss is finding Ging, his father and a Hunter himself. Believing that he will meet his father by becoming a Hunter, Gon takes the first step to walk the same path. During the Hunter Examination, Gon befriends the medical student Leorio Paladiknight, the vindictive Kurapika, and ex-assassin Killua Zoldyck. While their motives vastly differ from each other, they band together for a common goal and begin to venture into a perilous world.

For weeks, Atsushi Nakajima's orphanage has been plagued by a mystical tiger that only he seems to be unaware of. Suspected to be behind the strange incidents, the 18-year-old is abruptly kicked out of the orphanage and left hungry, homeless, and wandering through the city. While starving on a riverbank, Atsushi saves a rather eccentric man named Osamu Dazai from drowning. Whimsical suicide enthusiast and supernatural detective, Dazai has been investigating the same tiger that has been terrorizing the boy. Together with Dazai's partner Doppo Kunikida, they solve the mystery, but its resolution leaves Atsushi in a tight spot. As various odd events take place, Atsushi is coerced into joining their firm of supernatural investigators, taking on unusual cases the police cannot handle, alongside his numerous enigmatic co-workers.

In the coastal city of Naples, corruption is teeming—the police blatantly conspire with outlaws, drugs run rampant around the youth, and the mafia governs the streets with an iron fist. However, various fateful encounters will soon occur. Enter Giorno Giovanna, a 15-year-old boy with an eccentric connection to the Joestar family, who makes a living out of part-time jobs and pickpocketing. Furthermore, he is gifted with the unexplained Stand ability to give and create life—growing plants from the ground and turning inanimate objects into live animals, an ability he has dubbed Gold Experience. Fascinated by the might of local gangsters, Giorno has dreamed of rising up in their ranks and becoming a Gang-Star, a feat made possible by his encounter with Bruno Bucciarati, a member of the Passione gang with his own sense of justice. JoJo no Kimyou na Bouken: Ougon no Kaze follows the endeavors of Giorno after joining Bruno's team while working under Passione, fending off other gangsters and secretly plotting to overthrow their mysterious boss.

Raku Ichijou, a first-year student at Bonyari High School, is the sole heir to an intimidating yakuza family. Ten years ago, Raku made a promise to his childhood friend. Now, all he has to go on is a pendant with a lock, which can only be unlocked with the key which the girl took with her when they parted. Now, years later, Raku has grown into a typical teenager, and all he wants is to remain as uninvolved in his yakuza background as possible while spending his school days alongside his middle school crush Kosaki Onodera. However, when the American Bee Hive Gang invades his family's turf, Raku's idyllic romantic dreams are sent for a toss as he is dragged into a frustrating conflict: Raku is to pretend that he is in a romantic relationship with Chitoge Kirisaki, the beautiful daughter of the Bee Hive's chief, so as to reduce the friction between the two groups. Unfortunately, reality could not be farther from this whopping lie—Raku and Chitoge fall in hate at first sight, as the girl is convinced he is a pathetic pushover, and in Raku's eyes, Chitoge is about as attractive as a savage gorilla. Nisekoi follows the daily antics of this mismatched couple who have been forced to get along for the sake of maintaining the city's peace. With many more girls popping up his life, all involved with Raku's past somehow, his search for the girl who holds his heart and his promise leads him in more unexpected directions than he expects.