Suehara Maru is childhood best friends with one of Hozumino High School's most popular girls, Kuroha Shida. Cute, outgoing, and affectionate, Kuroha is the perfect older sister type. She has boys constantly begging at her feet to be with her. Yet, when she confesses to Suehara one day, he immediately rejects her; he just can't think of her in that way! Besides, he already has his sights set on his first love—school idol and renowned author Shirokusa Kachi. Suehara believes that he has a chance with Kachi after one fateful meeting, but soon, he finds out that Kachi has a boyfriend! With his dreams now shattered, Suehara agonizes over what could have been. That is, until Kuroha approaches him with a proposal: let's get revenge.

Perceived as strange and feared by man, over time the misshapen ones came to be known as Mushi. Although they harbor no ill intentions towards humans, many suffer from the side effects of their existence and strange nature; exploiting the Mushi without understanding them, even unintentionally, can lead to disaster and strife for any involved. Mushishi Zoku Shou continues the story of Mushishi Ginko on his journey to help the visible world to coexist with the Mushi. During his travels, Ginko discovers various gifted individuals—those cursed by circumstance and those maintaining a fragile symbiosis with the Mushi—inevitably confronting the question of whether humanity, talented and tortured alike, can manage the responsibility of the unseen. Moreover, as a Mushishi, Ginko must learn more about these strange beings and decide if he has the right to interfere with the complex relationships between Mushi and mankind.

The next phase of the controversial Blue Lock project is underway with the candidate pool being dwindled down to just 35. Out of the remaining strikers, only a select few will be chosen to play in an upcoming exhibition game against the current U-20 Japanese soccer team. Playing in this match comes with a caveat: winning will grant the players the right to represent the nation as the new U-20 team, but losing will bring an end to Blue Lock in its entirety. Among the ones left in the running is Yoichi Isagi, who is coming to terms with his own abilities. To further complicate matters, the six best players in the pool have already been named to the starting lineup and the remaining 29 will have to duke it out to claim a coveted spot. Each candidate must select a top six pairing to team up with for the selection to prove their competence. But if this mishmash of strikers wants to overthrow the current U-20 team, they will need to find a way to combine their playstyles effectively.

In a world inhabited by demons, cyclopes, and other fantastic creatures, humans stand apart as the outcasts. Quick to anger, the human race engaged in a war that all but wiped them out. The few humans that remain are seen as a delicacy, serving no purpose but to be hunted down and eaten. One day, a golem—a wandering protector of nature—encounters a lone human child while patrolling. Inspired by her enthusiasm, he takes the girl, named Somali, under his wing. Together, the duo embarks on a journey to find Somali's parents and bring her home.