The eccentric, self-proclaimed mad scientist Rintarou Okabe has become a shell of his former self. Depressed and traumatized after failing to rescue his friend Makise Kurisu, he has decided to forsake his mad scientist alter ego and live as an ordinary college student. Surrounded by friends who know little of his time travel experiences, Okabe spends his days trying to forget the horrors of his adventures alone. While working as a receptionist at a college technology forum, Okabe meets the short, spunky Maho Hiyajo, who later turns out to be the interpreter at the forum's presentation, conducted by Professor Alexis Leskinen. In front of a stunned crowd, Alexis and Maho unveil Amadeus—a revolutionary AI capable of storing a person's memories and creating a perfect simulation of that person complete with their personality and quirks. Meeting with Maho and Alexis after the presentation, Okabe learns that the two were Kurisu's colleagues in university, and that they have simulated her in Amadeus. Hired by Alexis to research the simulation's behavior, Okabe is given the chance to interact with the shadow of a long-lost dear friend. Dangerously tangled in the past, Okabe must face the harsh reality and carefully maneuver around the disastrous consequences that come with disturbing the natural flow of time.

After saving the Kingdom of Liones from the 10 Commandments, Meliodas and the Seven Deadly Sins are enjoying their time off. However, things aren't as peaceful as they seem, as the Sins are put through various trials to become strong enough to defeat the 10 Commandments and to overcome their past trauma. With help from past figures, the Sins are tasked with defeating the 10 Commandments and putting an end to their evil plans that began ten thousand years ago. The Sins begin to uncover the truth about each other, as well as those who stood before them. With this knowledge in hand, the battle against the 10 Commandments has only just begun. Nanatsu no Taizai: Kamigami no Gekirin continues to follow the Seven Deadly Sins and those that they meet on their journey. Through their adventures, they realize that their actions have had greater consequences on the present than they could have ever expected.

According to the Republic of San Magnolia, their ongoing war against the Giadian Empire has no casualties—however, that is mere propaganda. While the silver-haired Alba of the Republic's eighty-five sectors live safely behind protective walls, those of different appearances are interned in a secret eighty-sixth faction. Known within the military as the Eighty-Six, they are forced to fight against the Empire's autonomous Legion under the command of the Republican Handlers. Vladilena Milizé is assigned to the Spearhead squadron to replace their previous Handler. Shunned by her peers for being a fellow Eighty-Six supporter, she continues to fight against their inhumane discrimination. Shinei Nouzen is the captain of the Spearhead squadron. Infamous for being the sole survivor of every squadron he's been in, he insists on shouldering the names and wishes of his fallen comrades. When the fates of these young souls from two different worlds collide, will it ignite the spark that lights their path to salvation, or will they burn themselves in the flames of despair?

Tooru Honda has always been fascinated by the story of the Chinese zodiac that her beloved mother told her as a child. However, a sudden family tragedy changes her life, and subsequent circumstances leave her all alone. Tooru is now forced to live in a tent, but little does she know that her temporary home resides on the private property of the esteemed Souma family. Stumbling upon their home one day, she encounters Shigure, an older Souma cousin, and Yuki, the prince of her school. Tooru explains that she lives nearby, but the Soumas eventually discover her well-kept secret of being homeless when they see her walking back to her tent one night. Things start to look up for Tooru as they kindly offer to take her in after hearing about her situation. But soon after, she is caught up in a fight between Yuki and his hot-tempered cousin, Kyou. While trying to stop them, she learns that the Souma family has a well-kept secret of their own: whenever they are hugged by a member of the opposite sex, they transform into the animals of the Chinese zodiac. With this new revelation, Tooru will find that living with the Soumas is an unexpected adventure filled with laughter and romance.