Yukino Miyazawa is the female representative for her class and the most popular girl among the freshmen at her high school. Good at both academics and sports on top of being elegant and sociable, she has been an object of admiration all her life. However, in reality, she is an incredibly vain person who toils relentlessly to maintain her good grades, athleticism, and graceful appearance. She wants nothing more than to be the center of attention and praise—which is why she cannot stand Souichirou Arima, the male representative for her class and the only person more perfect than her. Since the first day of high school, she has struggled to steal the spotlight from her new rival but to no avail. At last, on the midterm exams, Yukino gets the top score and beats Souichirou. But, to her surprise, he congratulates her on her achievement, leading her to question her deceptive lifestyle. When Souichirou confesses his love to Yukino, she turns him down and gloats about it at home with only a hint of regret. But the very next day, Souichirou visits Yukino house to bring her a CD and sees her uninhibited self in action; now equipped with the truth, he blackmails her into completing his student council duties. Coerced into spending time with Souichirou, Yukino learns that she is not the only one hiding secrets.

Nemeses—powerful and mysterious demonic entities that fall from the sky and vaporize anything they touch. The only ones who can combat these creatures are Sorcerers, those who have survived an encounter with a Nemesis but were infected in the process. Seth, a Sorcerer from Pompo Hills, sets out on an adventure to exterminate all these Nemeses. Accompanying him are Doc and Mélie, fellow Sorcerers who share his ideal. Their main objective is to bring about a world where Sorcerers are no longer persecuted for being infected, and to that end, desire to destroy the source of the Nemeses themselves: the mythical Radiant.

Xian: the state of immortality that all cultivators strive to achieve. However, there is a dark energy that lies underneath—the forbidden Mo Dao, or demonic path. Through an unfortunate series of tragedies, this is the path that cultivator Wei Wuxian experiments with during his teachings. His rise in power is accompanied by chaos and destruction, but his reign of terror comes to an abrupt end when the cultivation clans overpower him and he is killed by his closest ally. Thirteen years later, Wei Wuxian is reincarnated in the body of a lunatic and reunited with Lan Wangji, a former classmate of his. This marks the beginning of a supernatural mystery that plagues the clans and threatens to disrupt their everyday life. Mo Dao Zu Shi follows these two men on their mission to unravel the mysteries of the spiritual world. Fighting demons, ghosts, and even other cultivators, the two end up forming a bond that neither of them had ever expected.

Due to poor lifestyle choices, a certain human's body is in constant turmoil. With germs, bacteria, and foreign substances abound, the jobs of various cells become increasingly difficult and dangerous. As some of the unfortunate ones who matured in this chaotic environment, Sekkekkyuu AA2153 and Hakkekkyuu U-1196 strive to fulfill their duties—even if it means seeing many of their fellow cells lose their lives in duty. Set in an environment vastly different from its parent story, Hataraku Saibou Black portrays the cells' struggles as they try to maintain the body's health. However, the human's condition continues to deteriorate, and whether or not these efforts will amount to something concrete depends on the cells!