Koyomi Araragi has recently survived a vampire attack and met several girls plagued by supernatural entities. On top of all this, he wakes up one morning to find himself kidnapped and tied up by his girlfriend Hitagi Senjougahara. Araragi's sister Karen has run afoul of Deishuu Kaiki, a swindler who once conned Senjougahara's family. As a result, Senjougahara has imprisoned Araragi to keep him safe from the devious Kaiki. But when Araragi receives a frantic message from Karen, he sets out to rescue her. Along with Karen's troubles, Tsukihi, Araragi's other server, faces issues of her own. And when two mysterious women step into their lives, not even Araragi can anticipate their true goals, nor the catastrophic truths about his family soon to be revealed.

The eccentric, self-proclaimed mad scientist Rintarou Okabe has become a shell of his former self. Depressed and traumatized after failing to rescue his friend Makise Kurisu, he has decided to forsake his mad scientist alter ego and live as an ordinary college student. Surrounded by friends who know little of his time travel experiences, Okabe spends his days trying to forget the horrors of his adventures alone. While working as a receptionist at a college technology forum, Okabe meets the short, spunky Maho Hiyajo, who later turns out to be the interpreter at the forum's presentation, conducted by Professor Alexis Leskinen. In front of a stunned crowd, Alexis and Maho unveil Amadeus—a revolutionary AI capable of storing a person's memories and creating a perfect simulation of that person complete with their personality and quirks. Meeting with Maho and Alexis after the presentation, Okabe learns that the two were Kurisu's colleagues in university, and that they have simulated her in Amadeus. Hired by Alexis to research the simulation's behavior, Okabe is given the chance to interact with the shadow of a long-lost dear friend. Dangerously tangled in the past, Okabe must face the harsh reality and carefully maneuver around the disastrous consequences that come with disturbing the natural flow of time.

After his confrontation in the Nether with his younger brother Shou, Shinra Kusakabe's resolve to become a hero that saves lives from the flame terror strengthens. Finding a way to turn the Infernals back into people, unraveling the mystery of the Evangelist and Adolla Burst, and saving his mother and Shou—these are the goals Shinra has in mind. However, he has come to realize that attaining these goals will not be easy, especially with the imminent danger the Evangelist poses. The Evangelist's plan is clear: to gather the eight pillars—the individuals who possess Adolla Burst—and sacrifice them to recreate the Great Cataclysm from 250 years ago. Having been revealed by the First Pillar that the birth of a new pillar is approaching, Shinra is determined to protect his fellow pillars from the Evangelist. Thus, the fiery battle between the Special Fire Force and the Evangelist ignites. Together with the Special Fire Force, Shinra's fight continues as he uncovers the truth about the Great Cataclysm and the nature of Adolla Bursts, as well as the mysteries behind human combustion.

Roaming the halls of the all-boys Sanada North High School are three close comrades: the eccentric ringleader with a hyperactive imagination Hidenori, the passionate Yoshitake, and the rational and prudent Tadakuni. Their lives are filled with giant robots, true love, and intense drama... in their colorful imaginations, at least. In reality, they are just an everyday trio of ordinary guys trying to pass the time, but who said everyday life couldn't be interesting? Whether it's an intricate RPG reenactment or an unexpected romantic encounter on the riverbank at sunset, Danshi Koukousei no Nichijou is rife with bizarre yet hilariously relatable situations that are anything but mundane.